Izuzquiza I, Jamtøy K A, Fossland N P, Martínez-Padilla I, Falahat F, Alou L, Prieto J, Gómez-Lus M L
Isabel Izuzquiza Avanzini, Área de Microbiología-Departamento de Medicina . Facultad de Medicina. Universidad Complutense de Madrid, Spain.
Rev Esp Quimioter. 2017 Feb;30(1):34-39. Epub 2016 Nov 22.
To assess whether there is a significant difference in infection rate after surgery tooth extraction in two different hospitals from Norway and Spain where different surgical antimicrobial prophylaxis protocols are applied.
An analytical observational study was conducted, retrospective cohorts type, analyzing healthy patients with no risk factors, who were third molar tooth operated in maxillofacial services of two different hospitals: St. Olav in Trondheim (Norway) and Clínico San Carlos in Madrid (Spain). The collected variables were: age, number of tooth removed, anesthesia type, and observations about the course of the operation registered in the clinical history. To assess the development of postoperative infection, patient's data of those who chose the hospital as the place to remove the suture thread were collected in Norway, whereas in Spain a telephone survey was conducted to determine the course of the operation months later.
In St. Olav Hospital 11.1% of patients operated received antibiotic regimen after surgery, while in Hospital San Carlos were 100%. The infection rate was 15% in St.Olav Hospital and 7.5% in Hospital San Carlos. These differences were no statistically significant.
The routine administration of antibiotics to healthy patients with no risk factors undergoing impacted third molar surgical removal is a common clinical practice which it does not seem to be justified.
评估在挪威和西班牙的两家不同医院，应用不同手术抗菌预防方案后，拔牙手术后的感染率是否存在显著差异。
进行了一项分析性观察研究，属于回顾性队列研究类型，分析无风险因素的健康患者，这些患者在两家不同医院的颌面外科接受了第三磨牙手术：挪威特隆赫姆的圣奥拉夫医院和西班牙马德里的圣卡洛斯临床医院。收集的变量包括：年龄、拔除牙齿数量、麻醉类型以及临床病史中记录的关于手术过程的观察结果。为评估术后感染的发生情况，在挪威收集了选择医院作为拆线地点的患者的数据，而在西班牙则进行了电话调查以确定数月后的手术情况。
在圣奥拉夫医院，11.1%接受手术的患者术后接受了抗生素治疗，而在圣卡洛斯医院这一比例为100%。圣奥拉夫医院的感染率为15%，圣卡洛斯医院为7.5%。这些差异无统计学意义。
对无风险因素的健康患者进行阻生第三磨牙手术拔除时常规使用抗生素是一种常见的临床做法，但似乎没有依据。
