Gil Salom M, Espi Macias A, Chuan Nuez P, Arenas Ricart J, Clar Blanch F, Carretero González P, García-Lomas J
Actas Urol Esp. 1989 May-Jun;13(3):171-6.
We studied the postoperative development of lymphocytes, T cells and lymphocyte subpopulations, in peripheral blood in 45 patients. Twenty-five of them were subjected to a TUR of a bladder tumor, 10 to a transvesical prostatectomy, 6 to a pyelolithotomy and 4 to a nephrectomy for renal atrophy secondary to lithiasis. We confirm a significant postoperative drop in the lymphocyte count and in the percentages of OKT 3+ (total T cells), OKT 4+ (helper T cells) and OKT 8+ cells (cytotoxic/suppressor T cells) 2-4 hours after the operation. Its duration varies according to the type of operation carried out. Despite the slight differences observed in the postoperative development of the lymphocyte subpopulations, at no time in the study did we report significant postoperative variations in the OKT 4+/OKT 8+ quotient.
我们研究了45例患者外周血中淋巴细胞、T细胞及淋巴细胞亚群的术后变化情况。其中25例行膀胱肿瘤经尿道切除术，10例行经膀胱前列腺切除术，6例行肾盂切开取石术，4例行因结石继发肾萎缩所致肾切除术。我们证实，术后2 - 4小时淋巴细胞计数以及OKT 3 +（总T细胞）、OKT 4 +（辅助性T细胞）和OKT 8 +细胞（细胞毒性/抑制性T细胞）百分比显著下降。其持续时间根据所施行手术的类型而有所不同。尽管在淋巴细胞亚群的术后变化中观察到细微差异，但在本研究中，我们未发现术后OKT 4 + /OKT 8 +比值有显著变化。
