Zilverschoon Marijn, Vincken Koen L, Bleys Ronald L A W
Department of Anatomy, University Utrecht, Medical Center, Utrecht, The Netherlands.
Image Sciences Institute, University Medical Center, Utrecht, The Netherlands.
J Biomed Inform. 2017 Jan;65:58-75. doi: 10.1016/j.jbi.2016.11.005. Epub 2016 Nov 21.
Virtual 3D models are powerful tools for teaching anatomy. At the present day, there are a lot of different digital anatomy models, most of these commercial applications are based on a 3D model of a human body reconstructed from images with a 1mm intervals. The use of even smaller intervals may result in more details and more realistic appearances of 3D anatomy models. The aim of this study was to create a realistic and highly detailed 3D model of the hand and wrist based on small interval cross-sectional images, suitable for undergraduate and postgraduate teaching purposes with the possibility to perform a virtual dissection in an educational application.
In 115 transverse cross-sections from a human hand and wrist, segmentation was done by manually delineating 90 different structures. With the use of Amira the segments were imported and a surface model/polygon model was created, followed by smoothening of the surfaces in Mudbox. In 3D Coat software the smoothed polygon models were automatically retopologied into a quadrilaterals formation and a UV map was added. In Mudbox, the textures from 90 structures were depicted in a realistic way by using photos from real tissue and afterwards height maps, gloss and specular maps were created to add more level of detail and realistic lightning on every structure. Unity was used to build a new software program that would support all the extra map features together with a preferred user interface.
A 3D hand model has been created, containing 100 structures (90 at start and 10 extra structures added along the way). The model can be used interactively by changing the transparency, manipulating single or grouped structures and thereby simulating a virtual dissection. This model can be used for a variety of teaching purposes, ranging from undergraduate medical students to residents of hand surgery. Studying the hand and wrist anatomy using this model is cost-effective and not hampered by the limited access to real dissecting facilities.
虚拟3D模型是解剖学教学的有力工具。目前,有许多不同的数字解剖模型,其中大多数商业应用基于间隔为1毫米的图像重建的人体3D模型。使用更小的间隔可能会使3D解剖模型呈现出更多细节和更逼真的外观。本研究的目的是基于小间隔横截面图像创建一个逼真且高度详细的手部和腕部3D模型,适用于本科和研究生教学,并有可能在教育应用中进行虚拟解剖。
在115个来自人手和腕部的横截面上,通过手动勾勒90个不同结构进行分割。使用Amira导入这些片段并创建表面模型/多边形模型,随后在Mudbox中对表面进行平滑处理。在3D Coat软件中,将平滑后的多边形模型自动重新拓扑成四边形结构并添加UV贴图。在Mudbox中,通过使用真实组织的照片以逼真的方式描绘90个结构的纹理,然后创建高度图、光泽和镜面反射图,为每个结构添加更多细节层次和逼真的光照效果。使用Unity构建一个新的软件程序,该程序将支持所有额外的贴图功能以及首选的用户界面。
已创建一个包含100个结构的3D手部模型(开始时有90个,过程中又添加了10个额外结构)。该模型可以通过改变透明度、操作单个或成组结构来进行交互式使用,从而模拟虚拟解剖。这个模型可用于多种教学目的,从本科医学生到手外科住院医师。使用该模型研究手部和腕部解剖学具有成本效益,且不受实际解剖设施获取有限的阻碍。