Cené Crystal W, Halladay Jacqueline R, Gizlice Ziya, Donahue Katrina E, Cummings Doyle M, Hinderliter Alan, Miller Cassandra, Johnson Larry F, Garcia Beverly, Tillman Jim, Little Edwin P, Rachide Marjorie R, Keyserling Thomas C, Ammerman Alice, Zhou Haibo, Wu Jia-Rong, DeWalt Darren
Department of Medicine, UNC Chapel Hill, Chapel Hill, NC, USA.
Cecil R. Sheps Center for Health Services Research, UNC Chapel Hill, Chapel Hill, NC, USA.
J Clin Hypertens (Greenwich). 2017 Apr;19(4):351-360. doi: 10.1111/jch.12944. Epub 2016 Nov 25.
The Southeastern United States has the highest prevalence of hypertension and African Americans have disproportionately worse blood pressure control. The authors sought to evaluate the effect of a multicomponent practice-based quality improvement intervention on lowering mean systolic blood pressure (SBP) at 12 and 24 months compared with baseline among 525 patients, and to assess for a differential effect of the intervention by race (African Americans vs white). At 12 months, both African Americans (-5.0 mm Hg) and whites (-7.8 mm Hg) had a significant decrease in mean SBP compared with baseline, with no significant between-group difference. Similarly, at 24 months, mean SBP decreased in both African Americans (-6.0 mm Hg) and whites (-7.2 mm Hg), with no significant difference between groups. Notably, no significant racial disparity in mean SBP at baseline was shown. The intervention was effective in lowering mean SBP in both African Americans and whites but there was no differential effect of the intervention by race.
美国东南部高血压患病率最高,非裔美国人的血压控制情况尤其糟糕。作者试图评估一项基于多成分实践的质量改进干预措施对525名患者在12个月和24个月时降低平均收缩压(SBP)的效果(与基线相比),并评估该干预措施在种族方面(非裔美国人与白人)的差异效果。在12个月时,与基线相比,非裔美国人(收缩压降低5.0毫米汞柱)和白人(收缩压降低7.8毫米汞柱)的平均收缩压均显著下降,组间无显著差异。同样,在24个月时,非裔美国人(收缩压降低6.0毫米汞柱)和白人(收缩压降低7.2毫米汞柱)的平均收缩压均下降,组间无显著差异。值得注意的是,基线时平均收缩压未显示出显著的种族差异。该干预措施在降低非裔美国人和白人的平均收缩压方面均有效,但在种族方面没有差异效果。