Fiscella Kevin, Holt Kathleen
Department of Family Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14620, USA.
Ann Fam Med. 2008 Nov-Dec;6(6):497-502. doi: 10.1370/afm.873.
Black Americans with hypertension have poorer blood pressure control than their white counterparts, but the impact of this disparity on mortality among black adults is not known. We assessed differences in systolic blood pressure (SBP) control among white and black adults with a diagnosis of hypertension, and measured the impact of that difference on cardiovascular and cerebrovascular mortality among blacks.
Using SBP measurements from white and black adults participating in the National Health and Nutrition Examination Survey, 1999-2002, we modeled changes in mortality rates resulting from a reduction of mean SBP among blacks to that of whites. Our data source for mortality estimates of blacks with hypertension was a meta-analysis of observational studies of SBP; our data source for reduction in mortality rates was a meta-analysis of SBP treatment trials.
The final sample of participants for whom SBP measurements were available included 1,545 black adults and 1,335 white adults. The mean SBP among blacks with hypertension was approximately 6 mm Hg higher than that for the total adult black population and 7 mm Hg higher than that for whites with hypertension. Within the hypertensive population, a reduction in mean SBP among blacks to that of whites would reduce the annual number of deaths among blacks from heart disease by 5,480 and from stroke by 2,190.
Eliminating racial disparity in blood pressure control among adults with hypertension would substantially reduce the number of deaths among blacks from both heart disease and stroke. Primary care clinicians should be particularly diligent when managing hypertension in black patients.
患有高血压的美国黑人在血压控制方面比白人更差,但这种差异对黑人成年人死亡率的影响尚不清楚。我们评估了被诊断患有高血压的白人和黑人成年人在收缩压(SBP)控制方面的差异,并测量了这种差异对黑人心血管和脑血管死亡率的影响。
利用1999 - 2002年参加国家健康与营养检查调查的白人和黑人成年人的SBP测量值,我们模拟了将黑人的平均SBP降至白人水平后死亡率的变化。我们用于估计患有高血压的黑人死亡率的数据源是对SBP观察性研究的荟萃分析;我们用于估计死亡率降低的数据来源是对SBP治疗试验的荟萃分析。
最终有SBP测量值的参与者样本包括1545名黑人成年人和1335名白人成年人。患有高血压的黑人的平均SBP比成年黑人总体高约6毫米汞柱,比患有高血压的白人高7毫米汞柱。在高血压人群中,将黑人的平均SBP降至白人水平可使黑人因心脏病每年死亡人数减少5480人,因中风每年死亡人数减少2190人。
消除高血压成年人中血压控制的种族差异将大幅减少黑人因心脏病和中风导致的死亡人数。在管理黑人患者的高血压时,初级保健临床医生应格外勤勉。