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含酒精的手部消毒剂能否降低军事部署期间急性腹泻的发生率?一项前瞻性随机试验。

Do alcohol-based hand rubs reduce the incidence of acute diarrhea during military deployments? A prospective randomized trial.

机构信息

French Military Center for Epidemiology and Public Health, Marseille, France.

French Military Center for Epidemiology and Public Health, Marseille, France.

出版信息

Travel Med Infect Dis. 2017 Jan-Feb;15:48-51. doi: 10.1016/j.tmaid.2016.11.007. Epub 2016 Nov 23.

DOI:10.1016/j.tmaid.2016.11.007
PMID:27890664
Abstract

BACKGROUND

Acute diarrhea remains a public health concern in armed forces deployed in tropical areas where access to water and soap is limited. This study aims to assess the effectiveness of alcohol-based hand rubs (ABHR) on incidence of diarrhea in poor hygiene conditions.

METHOD

A prospective randomized trial was conducted between November 2014 and January 2015 among French military troops deployed in Africa to compare a group of soldiers receiving usual hand hygiene recommendations (control group), to a group of soldiers who received ABHR in addition to usual hand hygiene recommendations (intervention group). Data on diarrhea and hygiene behaviors were collected using self-questionnaires. The incidence rate of diarrhea episodes in groups was compared.

RESULTS

Participation rate was 59% (236/400). The proportion of individuals who used ABHR was 97% in the intervention group and 62% in the control group. The overall incidence rate of diarrheal episodes was observed to be in the region of 60 per 100 persons-month without any significant difference between groups after adjustment on confounding factors (p = 0.93). Handwashing with soap was used on average 4 times a day in the control group and twice a day in the intervention group (p = 0.93). It was the only significant protective factor for diarrhea (p < 10).

CONCLUSION

Our results support that supplying soap and good quality water should be a priority on the field.

摘要

背景

在水资源和肥皂供应有限的热带地区部署的武装部队中,急性腹泻仍然是一个公共卫生关注点。本研究旨在评估酒精基手部消毒剂(ABHR)在卫生条件较差的情况下对腹泻发病率的影响。

方法

2014 年 11 月至 2015 年 1 月期间,在部署在非洲的法国军队中进行了一项前瞻性随机试验,将接受常规手部卫生建议的一组士兵(对照组)与接受 ABHR 加常规手部卫生建议的一组士兵(干预组)进行比较。使用自我问卷收集腹泻和卫生行为数据。比较两组腹泻发作的发生率。

结果

参与率为 59%(236/400)。干预组中使用 ABHR 的比例为 97%,对照组为 62%。在调整混杂因素后,两组之间的腹泻发作总体发生率无显著差异(p=0.93),为每 100 人-月 60 例。对照组平均每天洗手 4 次,干预组每天洗手 2 次(p=0.93)。这是唯一对腹泻有显著保护作用的因素(p<10)。

结论

我们的结果支持在现场优先供应肥皂和优质水。

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