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心脏骤停幸存者的心理健康及其与神经认知功能的关系。

Psychological wellbeing in survivors of cardiac arrest, and its relationship to neurocognitive function.

作者信息

Davies Siân E, Rhys Megan, Voss Sarah, Greenwood Rosemary, Thomas Matthew, Benger Jonathan R

机构信息

Behavioural and Clinical Neuroscience Institute, University of Cambridge, United Kingdom.

South Western Ambulance Service NHS Foundation Trust, United Kingdom.

出版信息

Resuscitation. 2017 Feb;111:22-25. doi: 10.1016/j.resuscitation.2016.11.004. Epub 2016 Nov 24.

DOI:10.1016/j.resuscitation.2016.11.004
PMID:27890777
Abstract

OBJECTIVE

To characterise psychological wellbeing in survivors of out-of-hospital cardiac arrest (OHCA), and examine its relationship to cognitive function.

PATIENTS

Forty-one highly functioning cardiac arrest survivors were drawn from the follow-up cohort of a randomised controlled trial of initial airway management in OHCA (ISRCTN:18528625).

DESIGN

Psychological wellbeing was assessed with a self-report questionnaire (the Depression Anxiety and Stress Scale; DASS) and cognitive function was examined using the Delayed Matching to Samples (DMS) test from the Cambridge Neuropsychological Test Automated Battery (CANTAB).

RESULTS

Mean anxiety levels were significantly higher in this patient group than normative data drawn from the general population (p=0.046). Multiple regression analyses showed that cognitive function, measured by the DMS, did not predict any of the DASS scales.

CONCLUSIONS

Anxiety plays an important role in determining perceived QoL in high functioning survivors, but psychological wellbeing is unrelated to cognitive function in this group. To achieve a comprehensive assessment of wellbeing, resuscitation research should consider outcomes beyond neurological function alone.

摘要

目的

描述院外心脏骤停(OHCA)幸存者的心理健康状况,并研究其与认知功能的关系。

患者

41名功能良好的心脏骤停幸存者来自OHCA初始气道管理随机对照试验的随访队列(国际标准随机对照试验编号:18528625)。

设计

采用自我报告问卷(抑郁焦虑压力量表;DASS)评估心理健康状况,并使用剑桥神经心理测试自动成套系统(CANTAB)中的延迟样本匹配(DMS)测试检查认知功能。

结果

该患者组的平均焦虑水平显著高于从普通人群中获取的标准数据(p = 0.046)。多元回归分析表明,用DMS测量的认知功能不能预测任何DASS量表。

结论

焦虑在决定功能良好的幸存者的感知生活质量方面起着重要作用,但该组的心理健康与认知功能无关。为了实现对健康状况的全面评估,复苏研究应考虑除神经功能之外的结果。

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