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Long-term outcomes after thiotepa-based high-dose therapy (HDT) and autologous hematopoietic cell transplantation (auto-HCT) in non-Hodgkin lymphoma (NHL).

作者信息

Shah N, Rauenzahn S, Veltri L, Wen S, Craig M, Hamadani M, Kanate A S, Cumpston A

机构信息

Osborn Hematopoietic Malignancy and Transplantation Program, West Virginia University, Morgantown, WV, USA.

Department of Internal Medicine, West Virginia University, Morgantown, WV, USA.

出版信息

Bone Marrow Transplant. 2017 Feb;52(2):321-322. doi: 10.1038/bmt.2016.275. Epub 2016 Nov 28.

DOI:10.1038/bmt.2016.275
PMID:27892948
Abstract
摘要

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Long-term outcomes after thiotepa-based high-dose therapy (HDT) and autologous hematopoietic cell transplantation (auto-HCT) in non-Hodgkin lymphoma (NHL).基于噻替派的大剂量疗法（HDT）及自体造血细胞移植（auto-HCT）治疗非霍奇金淋巴瘤（NHL）后的长期疗效。
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2
High-Dose Chemotherapy with Autologous Stem Cell Transplantation in Primary Central Nervous System Lymphoma: Data From the Japan Society for Hematopoietic Cell Transplantation Registry.原发性中枢神经系统淋巴瘤的大剂量化疗联合自体造血干细胞移植：来自日本造血细胞移植学会登记处的数据。
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Excessive toxicity of the high dose thiotepa and etoposide regimen when combined with radiation: Long-term autologous transplantation experience in follicular and mantle cell lymphoma.高剂量噻替哌和依托泊苷方案与放疗联合时的过度毒性：滤泡性和套细胞淋巴瘤的长期自体移植经验。
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Excessive toxicity of once daily i.v. BU, melphalan and thiotepa followed by auto SCT on patients with non-Hodgkin's lymphoma.非霍奇金淋巴瘤患者每日一次静脉注射白消安、美法仑和噻替派后进行自体造血干细胞移植，毒性过大。
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High-dose busulfan, melphalan, and thiotepa followed by autologous peripheral blood stem cell transplantation in patients with aggressive lymphoma or relapsed Hodgkin's disease.大剂量白消安、美法仑和噻替派序贯自体外周血干细胞移植用于侵袭性淋巴瘤或复发性霍奇金病患者。
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High-dose thiotepa, melphalan and carboplatin (TMCb) followed by autologous peripheral blood stem cell transplantation in patients with lymphoma -- a retrospective evaluation.大剂量噻替派、美法仑和卡铂（TMCb）序贯自体外周血干细胞移植治疗淋巴瘤患者——一项回顾性评估
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National Institutes of Health Hematopoietic Cell Transplantation Late Effects Initiative: The Subsequent Neoplasms Working Group Report.美国国立卫生研究院造血细胞移植迟发效应倡议：后续肿瘤工作组报告。
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本文引用的文献

1
Thiotepa-based high-dose therapy for autologous stem cell transplantation in lymphoma: a retrospective study from the EBMT.基于噻替派的高剂量疗法用于淋巴瘤自体干细胞移植：欧洲血液与骨髓移植组的一项回顾性研究
Bone Marrow Transplant. 2016 Feb;51(2):212-218. doi: 10.1038/bmt.2015.273. Epub 2015 Nov 16.
2
R-MPV followed by high-dose chemotherapy with TBC and autologous stem-cell transplant for newly diagnosed primary CNS lymphoma.利妥昔单抗维持血小板体积均值后，采用替莫唑胺进行大剂量化疗及自体干细胞移植治疗新诊断的原发性中枢神经系统淋巴瘤。
Blood. 2015 Feb 26;125(9):1403-10. doi: 10.1182/blood-2014-10-604561. Epub 2015 Jan 7.
3
Hematopoietic stem cell transplantation for non-Hodgkin lymphoma.
非霍奇金淋巴瘤的造血干细胞移植
Hematol Oncol Clin North Am. 2014 Dec;28(6):1073-95. doi: 10.1016/j.hoc.2014.08.015. Epub 2014 Sep 22.
4
Phase 2 trial of high-dose rituximab with high-dose cytarabine mobilization therapy and high-dose thiotepa, busulfan, and cyclophosphamide autologous stem cell transplantation in patients with central nervous system involvement by non-Hodgkin lymphoma.高剂量利妥昔单抗联合高剂量阿糖胞苷动员疗法及高剂量噻替派、白消安和环磷酰胺自体干细胞移植治疗非霍奇金淋巴瘤累及中枢神经系统患者的2期试验
Cancer. 2015 Jan 15;121(2):226-33. doi: 10.1002/cncr.29023. Epub 2014 Sep 9.
5
High-dose thiotepa, etoposide and carboplatin as conditioning regimen for autologous stem cell transplantation in patients with high-risk Hodgkin's lymphoma.大剂量噻替派、依托泊苷和顺铂作为高危霍奇金淋巴瘤患者自体干细胞移植的预处理方案。
Hematology. 2012 Jan;17(1):23-7. doi: 10.1179/102453312X13221316477534.
6
High-dose chemotherapy with autologous stem-cell transplantation and hyperfractionated radiotherapy as first-line treatment of primary CNS lymphoma.大剂量化疗联合自体干细胞移植及超分割放疗作为原发性中枢神经系统淋巴瘤的一线治疗方案
J Clin Oncol. 2006 Aug 20;24(24):3865-70. doi: 10.1200/JCO.2006.06.2117. Epub 2006 Jul 24.
7
Excessive toxicity of the high dose thiotepa and etoposide regimen when combined with radiation: Long-term autologous transplantation experience in follicular and mantle cell lymphoma.高剂量噻替哌和依托泊苷方案与放疗联合时的过度毒性：滤泡性和套细胞淋巴瘤的长期自体移植经验。
Leuk Lymphoma. 2005 Oct;46(10):1441-8. doi: 10.1080/10428190500144656.
8
High dose chemotherapy with thiotepa, mitoxantrone and carboplatin (TMJ) followed by autologous stem cell support in 100 consecutive lymphoma patients in a single centre: analysis of efficacy, toxicity and prognostic factors.在单一中心对100例连续的淋巴瘤患者进行高剂量噻替派、米托蒽醌和顺铂（TMJ）化疗，随后给予自体干细胞支持：疗效、毒性及预后因素分析
Leuk Lymphoma. 2004 Nov;45(11):2253-9. doi: 10.1080/10428190410001723250.
9
High-dose thiotepa, melphalan and carboplatin (TMCb) followed by autologous peripheral blood stem cell transplantation in patients with lymphoma -- a retrospective evaluation.大剂量噻替派、美法仑和卡铂（TMCb）序贯自体外周血干细胞移植治疗淋巴瘤患者——一项回顾性评估
Bone Marrow Transplant. 2004 Nov;34(9):781-6. doi: 10.1038/sj.bmt.1704672.
10
A novel preparative regimen for autologous transplant in non-Hodgkin's lymphoma: long-term experience with etoposide and thiotepa.非霍奇金淋巴瘤自体移植的一种新型预处理方案：依托泊苷和噻替派的长期经验
Bone Marrow Transplant. 2004 Jan;33(1):19-24. doi: 10.1038/sj.bmt.1704312.