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[一种新的风湿病免疫遗传标记物]

[A new immunogenetic marker of rheumatism].

作者信息

Kilasoniia L O, Chumburidze V B, Tatishvili N I, Polianskaia I S, Tsitlanadze V G

出版信息

Klin Med (Mosk). 1989 Jun;67(6):64-6.

PMID:2789313
Abstract

Use of monoclonal D8/17 antiserum was studied for identification of B-cell antigen in 44 rheumatic fever patients. The control group comprised healthy subjects (30) and patients suffering from rheumatoid arthritis (30), ischemic heart disease (IO); chronic tonsillitis (12) and different neoplasma of the brain (10). The preliminary genetic analysis of these patients has shown that monoclonal antiserum D8/17 can identify B-cell marker in 88-100 per cent of rheumatic fever cases.

摘要

研究了单克隆D8/17抗血清在44例风湿热患者中鉴定B细胞抗原的应用。对照组包括健康受试者(30例)和患有类风湿性关节炎(30例)、缺血性心脏病(10例)、慢性扁桃体炎(12例)及不同脑肿瘤(10例)的患者。对这些患者的初步基因分析表明,单克隆抗血清D8/17可在88%-100%的风湿热病例中鉴定出B细胞标志物。

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[A new immunogenetic marker of rheumatism].[一种新的风湿病免疫遗传标记物]
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