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地塞米松在下颌第三磨牙手术切除过程中在咬肌中的应用。

Application of Dexamethasone in the Masseter Muscle During the Surgical Removal of Lower Third Molars.

作者信息

Rocha-Neto Alípio Miguel, Nogueira Emerson Filipe de Carvalho, Borba Patrícia Mendonça, Laureano-Filho José Rodrigues, Vasconcelos Belmiro Cavalcanti do Egito

机构信息

*Department of Oral and Maxillofacial Surgery †Orofacial Pain Department, University of Pernambuco, Recife, Brazil.

出版信息

J Craniofac Surg. 2017 Jan;28(1):e43-e47. doi: 10.1097/SCS.0000000000003188.

Abstract

PURPOSE

The aim of the present study was to analyze the effect of the application of dexamethasone in the masseter muscle during third molar surgery.

METHODS

This randomized, clinical trial used dependent samples and the split-mouth method. A sample of 30 patients, with impacted or semi-impacted third molars, as well as vertical and mesioangular positions of a similar surgical difficulty (on both sides), was subjected to 2 operations: an experimental operation and a control procedure, with a 30-day wash-out. The choice of which group would be experimental or control was random. The experimental group received 8 mg of dexamethasone, which was applied directly to the masseter muscle immediately after surgery. The control group did not receive corticosteroids. Seven and 15 days after the surgery, the patients were assessed in relation to their levels of pain, trismus, and edema.

RESULTS

Concerning edema and trismus, there was a significant difference (P <0.05) between the control and experimental groups. As for the pain scale, no significant differences were found between the presence or absence of corticoids.

CONCLUSION

The present study concluded that the application of dexamethasone in the masseter muscle effectively reduces edema and trismus, but does not affect pain.

摘要

目的

本研究旨在分析在第三磨牙手术中地塞米松应用于咬肌的效果。

方法

本随机临床试验采用相关样本和双侧对照法。选取30例患有阻生或半阻生第三磨牙且手术难度相似(两侧)的垂直位和近中倾斜位患者,进行两次手术:一次实验性手术和一次对照手术,间隔30天洗脱期。实验组和对照组的分组是随机的。实验组在手术后立即将8毫克地塞米松直接注射到咬肌中。对照组未接受皮质类固醇治疗。术后7天和15天,对患者的疼痛、张口受限和水肿程度进行评估。

结果

在水肿和张口受限方面,对照组和实验组之间存在显著差异(P<0.05)。在疼痛评分方面,使用或未使用皮质类固醇之间未发现显著差异。

结论

本研究得出结论,地塞米松应用于咬肌可有效减轻水肿和张口受限,但不影响疼痛。

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