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袖状胃切除术联合简化希尔修复术治疗病态肥胖症和胃食管反流病:14例患者的初步结果

Sleeve Gastrectomy Combined with the Simplified Hill Repair in the Treatment of Morbid Obesity and Gastro-esophageal Reflux Disease: Preliminary Results in 14 Patients.

作者信息

Gero Daniel, Ribeiro-Parenti Lara, Arapis Konstantinos, Marmuse Jean-Pierre

机构信息

Department of General and Digestive Surgery, University Hospital Bichat - Claude-Bernard, 46 Rue Henri Huchard, 75018, Paris, France.

出版信息

World J Surg. 2017 Apr;41(4):1035-1039. doi: 10.1007/s00268-016-3829-y.

Abstract

BACKGROUND

Our aim is to report our initial experience with a novel technique which addresses morbid obesity and gastro-esophageal reflux disease (GERD) simultaneously by combination of laparoscopic sleeve gastrectomy (LSG) and simplified laparoscopic Hill repair (sLHR).

METHODS

Retrospective analysis of LSG+sLHR patients >5 months postoperatively includes demographics, GERD status, proton-pump inhibitor (PPI) use, body mass index (BMI), excess BMI loss (EBMIL), complications and GERD-Health Related Quality of Life (GERD-HRQL) questionnaire. LSG+sLHR surgical technique: posterior cruroplasty,  standard LSG, fixation of the esophagogastric junction to the median arcuate ligament.

RESULTS

Fourteen patients underwent LSG+sLHR [12 women and 2 men, mean (range) age 47 years (27-57), BMI 41 kg/m (35-65)]. Five patients had previous gastric banding (GB). All had symptomatic GERD confirmed by gastroscopy and/or upper-gastrointestinal contrast study, two with chronic cough, 10 took PPI daily. Twelve had hiatus hernia and two patulous cardia at surgical exploration. Associated interventions were three GB removals and one cholecystectomy. Postoperative complication was one surgical site infection. Follow-up of all patients at median 12.5 months (5-17) is as follows: symptomatic GERD 3/14 patients, chronic cough 0/14, daily PPI use in 1/14, mean EBMIL 68% (17-120), satisfaction 93%, mean GERD-HRQL score 3,28/50 (0-15), with 4 patients 0/50, occasional bloatedness in 2 patients and dysphagia not reported.

CONCLUSION

The novel technique which combines LSG with sLHR is feasible, safe and can be associated with GB removal. Preliminary results showed patient satisfaction, high remission rate of preexisting GERD, decrease in PPI use and unimpaired weight loss. Further evaluation is necessary in a controlled and staged manner to establish the technique's real effectiveness.

摘要

背景

我们的目的是报告一种新技术的初步经验,该技术通过腹腔镜袖状胃切除术(LSG)和简化腹腔镜希尔修复术(sLHR)相结合,同时解决病态肥胖和胃食管反流病(GERD)。

方法

对术后超过5个月的LSG + sLHR患者进行回顾性分析,包括人口统计学、GERD状况质子泵抑制剂(PPI)使用情况、体重指数(BMI)、超重BMI减轻(EBMIL)、并发症以及GERD健康相关生活质量(GERD - HRQL)问卷。LSG + sLHR手术技术:后交叉成形术、标准LSG、食管胃交界处固定于正中弓状韧带。

结果

14例患者接受了LSG + sLHR手术[12例女性和2例男性,平均(范围)年龄47岁(27 - 57岁),BMI 41kg/m²(35 - 65)]。5例患者曾接受过胃束带术(GB)。所有患者经胃镜检查和/或上消化道造影研究确诊为有症状的GERD,2例有慢性咳嗽,10例每天服用PPI。手术探查时,12例有食管裂孔疝,2例贲门松弛。相关干预措施包括3例拆除胃束带和1例胆囊切除术。术后并发症为1例手术部位感染。所有患者的中位随访时间为12.5个月(5 - 17个月),结果如下:有症状的GERD患者3/14例,慢性咳嗽患者0/14例,每天服用PPI的患者1/14例,平均EBMIL为68%(17 - 120),满意度为93%,平均GERD - HRQL评分为3.28/50(0 - 15),4例患者评分为0/50,2例患者偶尔有腹胀,未报告有吞咽困难。

结论

将LSG与sLHR相结合的新技术是可行、安全的,并且可以与拆除胃束带相关联。初步结果显示患者满意度高、既往GERD缓解率高、PPI使用减少且体重减轻未受影响。有必要以对照和分阶段的方式进行进一步评估,以确定该技术的实际有效性。

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