Ece Ilhan, Yilmaz Huseyin, Acar Fahrettin, Colak Bayram, Yormaz Serdar, Sahin Mustafa
Department of Surgery, Faculty of Medicine, Selcuk University, 42075, Konya, Turkey.
Obes Surg. 2017 Jun;27(6):1460-1465. doi: 10.1007/s11695-016-2518-0.
Laparoscopic sleeve gastrectomy (LSG) is one of the most prefered treatment option for morbid obesity. However, the effects of LSG on gastroesophageal reflux disease (GERD) are controversial. Asymptomatic GERD and hiatal hernia (HH) is common in obese patients. Therefore, it is important to identify the high risk patients prior to surgery. This study aims to evaluate efficacy of cruroplasty for HH during LSG in morbidly obese patients using ambulatory pH monitoring (APM) results, and to investigate the patients' selection criteria for this procedure.
This retrospective study includes outcomes of 59 patients who underwent LSG and HH repair according to our patient selection algorithm. Outcomes included preoperative GERD Health-Related Quality of Life (GERD-HRQL) questionnaire, APM results, percentage of postoperative excess weight loss, and total weight loss.
For a total of 402 patients, APM was applied in 70 patients who had a positive score of GERD-HRQL, and 59 patients underwent LSG and concomitant HH repair who had a DeMeester score of 14.7% or above. There was no statistically significant difference in weight loss at 6 and 12-month follow-up. Two patients (3.3%) had symptoms of GERD at 12 months postoperatively, and only one (1.6%) patient required treatment of proton pump inhibitor for reflux. In the total cohort, 11 (2.7%) patients also evolved de novo GERD symptoms.
This study confirm that careful attention to patient selection and surgical technique can reduce the symptoms of GERD at short-term. Routine bilateral crus exploration could be a major risk factor of postoperative GERD.
腹腔镜袖状胃切除术(LSG)是治疗病态肥胖最常用的手术方式之一。然而,LSG对胃食管反流病(GERD)的影响存在争议。无症状GERD和食管裂孔疝(HH)在肥胖患者中很常见。因此,术前识别高危患者很重要。本研究旨在利用动态pH监测(APM)结果评估LSG术中HH修补术对病态肥胖患者的疗效,并探讨该手术的患者选择标准。
这项回顾性研究纳入了59例根据我们的患者选择算法接受LSG和HH修补术的患者的结果。结果包括术前GERD健康相关生活质量(GERD-HRQL)问卷、APM结果、术后超重减轻百分比和总体体重减轻情况。
在总共402例患者中,70例GERD-HRQL评分呈阳性的患者接受了APM,59例接受LSG并同时进行HH修补术的患者DeMeester评分在14.7%及以上。在6个月和12个月的随访中,体重减轻情况无统计学显著差异。2例患者(3.3%)术后12个月出现GERD症状,只有1例(1.6%)患者因反流需要质子泵抑制剂治疗。在整个队列中,11例(2.7%)患者也出现了新发GERD症状。
本研究证实,仔细关注患者选择和手术技术可在短期内减轻GERD症状。常规双侧膈脚探查可能是术后GERD的主要危险因素。