基层医疗医生为注射吸毒者开具艾滋病病毒暴露前预防药物的意愿。
Primary Care Physicians' Willingness to Prescribe HIV Pre-exposure Prophylaxis for People who Inject Drugs.
作者信息
Edelman E Jennifer, Moore Brent A, Calabrese Sarah K, Berkenblit Gail, Cunningham Chinazo, Patel Viraj, Phillips Karran, Tetrault Jeanette M, Shah Minesh, Fiellin David A, Blackstock Oni
机构信息
Yale University School of Medicine, 367 Cedar Street, ESH A, suite 401, New Haven, CT, 06510, USA.
Center for Interdisciplinary Research on AIDS, Yale University School of Public Health, New Haven, CT, USA.
出版信息
AIDS Behav. 2017 Apr;21(4):1025-1033. doi: 10.1007/s10461-016-1612-6.
Abstract
Pre-exposure prophylaxis for HIV (PrEP) is recommended for people who inject drugs (PWID). Despite their central role in disease prevention, willingness to prescribe PrEP to PWID among primary care physicians (PCPs) is largely understudied. We conducted an online survey (April-May 2015) of members of a society for academic general internists regarding PrEP. Among 250 respondents, 74% (n = 185) of PCPs reported high willingness to prescribe PrEP to PWID. PCPs were more likely to report high willingness to prescribe PrEP to all other HIV risk groups (p's < 0.03 for all pair comparisons). Compared with PCPs delivering care to more HIV-infected clinic patients, PCPs delivering care to fewer HIV-infected patients were more likely to report low willingness to prescribe PrEP to PWID (Odds Ratio [95% CI] = 6.38 [1.48-27.47]). PCP and practice characteristics were not otherwise associated with low willingness to prescribe PrEP to PWID. Interventions to improve PCPs' willingness to prescribe PrEP to PWID are needed.
摘要
建议为注射吸毒者（PWID）提供艾滋病病毒暴露前预防（PrEP）。尽管PrEP在疾病预防中发挥着核心作用，但对于初级保健医生（PCP）向PWID开具PrEP处方的意愿，人们对此研究甚少。我们于2015年4月至5月对一个学术普通内科医生协会的成员进行了一项关于PrEP的在线调查。在250名受访者中，74%（n = 185）的初级保健医生表示非常愿意为PWID开具PrEP处方。与向所有其他艾滋病病毒风险群体开具PrEP处方相比，初级保健医生表示更愿意为PWID开具PrEP处方（所有配对比较的p值均<0.03）。与为更多艾滋病病毒感染门诊患者提供治疗的初级保健医生相比，为较少艾滋病病毒感染患者提供治疗的初级保健医生更有可能表示不太愿意为PWID开具PrEP处方（优势比[95%置信区间]=6.38[1.48 - 27.47]）。初级保健医生和执业特征在其他方面与不太愿意为PWID开具PrEP处方无关。需要采取干预措施来提高初级保健医生为PWID开具PrEP处方的意愿。
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