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美国青少年健康提供者对有感染 HIV 风险的青少年开具暴露前预防(PrEP)药物的意愿。

Adolescent Health Providers' Willingness to Prescribe Pre-Exposure Prophylaxis (PrEP) to Youth at Risk of HIV Infection in the United States.

机构信息

Department of Pediatrics, UCSF-Benioff Children's Hospital, University of California, San Francisco, California.

Department of Epidemiology and Biostatistics, University of California, San Francisco, California.

出版信息

J Adolesc Health. 2018 Aug;63(2):242-244. doi: 10.1016/j.jadohealth.2018.03.016. Epub 2018 May 26.

DOI:10.1016/j.jadohealth.2018.03.016
PMID:29843969
Abstract

PURPOSE

HIV disproportionately affects young men who have sex with men. Pre-exposure prophylaxis (PrEP) can prevent HIV acquisition; however, youth access to PrEP is limited by provider willingness to prescribe PrEP.

METHODS

We conducted an online survey of clinicians working with adolescents (aged 13-17 years) and young adults (aged 18-26 years) in the United States through the Society of Adolescent Health and Medicine. We used multivariate logistic regression to assess provider beliefs associated with willingness to provide PrEP.

RESULTS

Nearly all (93.2%) providers had heard of PrEP, and 57 (35.2%) had prescribed PrEP. While almost all providers (95%) agreed that PrEP prevents HIV, fewer were willing to prescribe to young adults (77.8%) or adolescents (64.8%). Willingness to prescribe PrEP was strongly associated with the belief that providers had enough knowledge to safely provide PrEP to adolescents (OR 2.11, confidence interval [CI]: 1.18-3.76, p = .01) and young adults (odds ratio 5.19, CI: 2.15-12.50, p ≤ .001), and that adolescents would be adherent (odds ratio 3, CI: 1.30-6.90, p = .01). Response rate was 17%.

CONCLUSIONS

Almost all providers had heard of PrEP and most providers were willing to prescribe PrEP. Provider education and tools to promote provider self-efficacy and adolescent adherence might improve provider willingness to provide PrEP.

摘要

目的

艾滋病毒在男男性行为者中不成比例地影响年轻人。暴露前预防(PrEP)可以预防艾滋病毒的感染;然而,青年获得 PrEP 的机会受到提供者提供 PrEP 意愿的限制。

方法

我们通过美国青少年健康医学学会对在美国为青少年(13-17 岁)和年轻成年人(18-26 岁)提供服务的临床医生进行了一项在线调查。我们使用多变量逻辑回归来评估与提供 PrEP 的意愿相关的提供者信念。

结果

几乎所有(93.2%)的提供者都听说过 PrEP,57 名(35.2%)提供者曾开具 PrEP。虽然几乎所有的提供者(95%)都认为 PrEP 可以预防艾滋病毒,但愿意为年轻人(77.8%)或青少年(64.8%)开具 PrEP 的人则较少。愿意开具 PrEP 的意愿与提供者认为自己有足够的知识为青少年(OR 2.11,置信区间 [CI]:1.18-3.76,p =.01)和年轻成年人(OR 5.19,CI:2.15-12.50,p ≤.001)安全提供 PrEP 的信念以及青少年的依从性(OR 3,CI:1.30-6.90,p =.01)密切相关。回复率为 17%。

结论

几乎所有的提供者都听说过 PrEP,大多数提供者都愿意开具 PrEP。提供者教育和工具可以提高提供者的自我效能感和青少年的依从性,从而改善提供者提供 PrEP 的意愿。

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