le Nobel Gavin John, James Adrian Lewis
Department of Otolaryngology Head and Neck Surgery, University of Toronto, Toronto, Canada.
J Int Adv Otol. 2016 Dec;12(3):332-336. doi: 10.5152/iao.2016.2838. Epub 2016 Nov 28.
Potassium-titanyl-phosphage (KTP) lasers possess many characteristics suitable for otologic surgery. The objective of this report is to provide recommendations on the use of KTP laser for cholesteatoma surgery based on a narrative review of currently available evidence. PubMed and the Cochrane Review of randomized control trials were searched for relevant publications on efficacy and adverse effects and relevant articles appraised by the authors using Oxford Centre for Evidence-based Medicine criteria for recommendations. The potential benefits of KTP laser in cholesteatoma surgery include reduced rates of residual cholesteatoma and improved hearing outcomes. Cholesteatoma may be more effectively removed using KTP laser than using mechanical dissection alone. Reduced rates of residual cholesteatoma have been reported with KTP laser with level 2 evidence. In addition, KTP laser may facilitate the removal of cholesteatoma without the risk of mechanical trauma. This potentially allows for improved postoperative hearing outcomes through a) minimizing cochlear trauma and reducing sensorineural hearing loss and b) reducing the need for disruption of an intact ossicular chain. Currently, level 4 evidence exists to support improved postoperative hearing outcomes with the use of KTP laser. KTP laser use appears to be safe in otologic surgery if appropriate guidelines are followed. Current evidence is sufficient to strongly recommend KTP laser use for the prevention of residual cholesteatoma (Grade B recommendation) and an option for KTP laser use for optimizing hearing outcomes (Grade C recommendation).
磷酸钛氧钾(KTP)激光具有许多适用于耳科手术的特性。本报告的目的是基于对现有证据的叙述性综述,就KTP激光在胆脂瘤手术中的应用提供建议。检索了PubMed和Cochrane随机对照试验综述,以查找有关疗效和不良反应的相关出版物,并由作者使用牛津循证医学中心的推荐标准对相关文章进行评估。KTP激光在胆脂瘤手术中的潜在益处包括降低残余胆脂瘤的发生率和改善听力结果。使用KTP激光可能比单独使用机械剥离更有效地清除胆脂瘤。有二级证据表明,KTP激光可降低残余胆脂瘤的发生率。此外,KTP激光可能有助于清除胆脂瘤,而无机械创伤风险。这可能通过以下方式改善术后听力结果:a)将耳蜗创伤降至最低并减少感音神经性听力损失;b)减少破坏完整听骨链的必要性。目前,有四级证据支持使用KTP激光可改善术后听力结果。如果遵循适当的指南,KTP激光在耳科手术中似乎是安全的。现有证据足以强烈推荐使用KTP激光预防残余胆脂瘤(B级推荐),并将其作为优化听力结果的一种选择(C级推荐)。