Block B S, Parer J T, Llanos A J, Court D J
Department of Obstetrics and Gynecology, University of Chicago.
Biol Neonate. 1989;56(2):94-100. doi: 10.1159/000243108.
Surgical procedures which involve the pregnant uterus are associated with preterm labor contractions in the postoperative period. Because uterine contractions decrease fetal oxygen tension, we investigated the effect of maternal ritodrine infusion on fetal oxygen consumption in catheterized fetal sheep 5 h postoperatively. During ritodrine infusion, uterine activity promptly abated, but the oxygen tension in the umbilical vein and descending aorta decreased. The arterial-venous oxygen content difference, the umbilical blood flow, and consequently, fetal oxygen consumption did not change significantly. We conclude that fetal oxygenation is not improved by eliminating uterine activity with maternal ritodrine infusion in the postoperative period.
涉及妊娠子宫的外科手术与术后早产宫缩有关。由于子宫收缩会降低胎儿氧分压，我们研究了术后5小时给母体输注利托君对导管插入的胎羊胎儿氧消耗的影响。在输注利托君期间，子宫活动迅速减弱，但脐静脉和降主动脉中的氧分压降低。动静脉氧含量差、脐血流量以及胎儿氧消耗均无显著变化。我们得出结论，术后通过给母体输注利托君消除子宫活动并不能改善胎儿氧合。
