磁共振成像在乳腺癌术前分期中的应用：我们的经验

Magnetic Resonance Imaging in the Pre-Surgical Staging of Breast Cancer: Our Experience.

作者信息

Rabasco Paola, Caivano Rocchina, Dinardo Giuseppina, Gioioso Matilde, Lotumolo Antonella, Iannelli Giancarlo, Villonio Antonio, La Torre Giuseppe, D'Errico Stefano, Macarini Luca, Guglielmi Giuseppe, Cammarota Aldo

机构信息

a IRCCS-CROB , Rionero in Vulture , Italy.

b Department of Radiology , University of Foggia , Foggia , Italy.

出版信息

Cancer Invest. 2017 Jan 2;35(1):43-50. doi: 10.1080/07357907.2016.1251943. Epub 2016 Nov 30.

DOI:10.1080/07357907.2016.1251943

PMID:27901596

Abstract

PURPOSE

To investigate the clinical impact of magnetic resonance imaging (MRI) in the detection of multifocal-multicentric breast cancers, already identified by mammography and ultrasound, and analyzed histologically, to evaluate its role in preoperative staging.

MATERIALS AND METHODS

From January 2012 to February 2014, 188 patients, aged 28 to 74 years, newly diagnosed with breast cancer on conventional imaging (mammography and ultrasound) were enrolled. They underwent preoperative contrast-enhanced 3T MRI. Patients underwent surgery according to international guidelines. Results of all diagnostic procedures were compared.

RESULTS

Among the 188 patients, 163 (87%) had a unilateral and unifocal tumor at both conventional imaging; MRI diagnosed 22/22 (100%) of multifocal and multicentric tumors, the combination of mammography and ultrasound diagnosed 12/22 (54%), and mammography alone diagnosed 8/22 (36%) multifocal and multicentric tumors. MRI prompted a change in surgical strategy in 10/188 (5%) patients. This change comprised mastectomy instead of conservative surgery (n = 7) and more extensive conservative surgery (n = 3).

CONCLUSIONS

MRI was confirmed to show higher sensitivity than conventional imaging in detecting multifocal and multicentric breast cancers.

摘要

目的

探讨磁共振成像（MRI）在检测已通过乳腺X线摄影和超声检查发现并经组织学分析的多灶性-多中心性乳腺癌中的临床影响，以评估其在术前分期中的作用。

材料与方法

2012年1月至2014年2月，纳入188例年龄在28至74岁之间、经传统成像（乳腺X线摄影和超声）新诊断为乳腺癌的患者。他们接受了术前3T对比增强MRI检查。患者根据国际指南接受手术。比较所有诊断程序的结果。

结果

在188例患者中，163例（87%）在两种传统成像检查中均为单侧单灶性肿瘤；MRI诊断出22例多灶性和多中心性肿瘤中的22例（100%），乳腺X线摄影和超声联合诊断出12例（54%），单独乳腺X线摄影诊断出8例（36%）多灶性和多中心性肿瘤。MRI促使10/188例（5%）患者的手术策略发生改变。这种改变包括将乳房切除术改为保乳手术（n = 7）和更广泛的保乳手术（n = 3）。