[母体肺部实验性炎症中胎儿及新生儿肺Ⅱ型肺泡上皮细胞表面活性物质的表面活性及超微结构变化]
[Surfactant surface activity and ultrastructural changes in the type-II alveolocytes of fetal and neonatal lungs in experimental inflammation of the maternal lungs].
作者信息
Zagorul'ko A K, Fat L F, Safronova L G, Kobozev G V, Gorelik N I
出版信息
Biull Eksp Biol Med. 1989 Jun;107(6):753-6.
PMID:2790177
Abstract
The lungs of 19 guinea pigs, born from 8 females in which acute and chronic pneumonia had been modelled by transtracheal introduction of sterile fishing-line were investigated. It was established, that in guinea pigs, born in females with acute and chronic pneumonia, the functional immaturity of pneumocytes of the 2-nd type took place. The functional immaturity of pneumocytes of the 2-nd type results in suppression of the surface active characteristics of surfactant.
摘要
对19只豚鼠的肺部进行了研究，这些豚鼠由8只雌性豚鼠所生，通过经气管引入无菌钓鱼线对这些雌性豚鼠进行了急性和慢性肺炎建模。结果发现，在患有急性和慢性肺炎的雌性豚鼠所生的豚鼠中，出现了Ⅱ型肺细胞功能不成熟的情况。Ⅱ型肺细胞功能不成熟导致表面活性剂的表面活性特征受到抑制。
相似文献
1
2
[The pulmonary surfactant status in lung immaturity].[肺发育不成熟时的肺表面活性物质状态]
Arkh Patol. 1990;52(2):10-4.
3
[Ultrastructure of the blood-air barrier in comparison with the indices of surfactant surface activity].
Biull Eksp Biol Med. 1988 Nov;106(11):617-21.
4
5
6
Ultrastructural evaluation of type II pneumocytes in the hypoplastic lung of rabbit fetuses induced by oligohydramnios.羊水过少诱导的兔胎儿肺发育不全中II型肺细胞的超微结构评估
J Obstet Gynaecol Res. 2007 Dec;33(6):777-80. doi: 10.1111/j.1447-0756.2007.00655.x.
7
[Pulmonary surfactant system of newborn rats in alcoholic intoxication of pregnant rats].[孕鼠酒精中毒时新生大鼠的肺表面活性物质系统]
Biull Eksp Biol Med. 1990 Aug;110(8):142-4.
8
Ultrastructural features of alveolar epithelial cells in the late fetal pulmonary acinus: a comparison between normal and hypoplastic lungs using a rat model of pulmonary hypoplasia and congenital diaphragmatic hernia.胎儿肺腺泡晚期肺泡上皮细胞的超微结构特征：使用肺发育不全和先天性膈疝大鼠模型对正常肺和发育不全肺的比较
Microsc Res Tech. 1993 Dec 1;26(5):389-99. doi: 10.1002/jemt.1070260507.
9
Zotero 插件