老年HIV阳性成年人中与HIV相关的羞耻感及健康相关生活质量
HIV-related shame and health-related quality of life among older, HIV-positive adults.
作者信息
Vincent Wilson, Fang Xindi, Calabrese Sarah K, Heckman Timothy G, Sikkema Kathleen J, Hansen Nathan B
机构信息
Department of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, CA, USA.
School of Public Health, Yale University, New Haven, CT, USA.
出版信息
J Behav Med. 2017 Jun;40(3):434-444. doi: 10.1007/s10865-016-9812-0. Epub 2016 Nov 30.
This study investigated how HIV-related shame is associated with health-related quality of life (HRQoL) in older people living with HIV (PLHIV). Structural equation modeling tested whether HIV-related shame was associated with three dimensions of HRQoL (physical, emotional, and social well-being) and whether there were significant indirect associations of HIV-related shame with the three HRQoL dimensions via depression and loneliness in a sample of 299 PLHIV ≥50 years old. Results showed that depression and loneliness were key mechanisms, with depression at least partially accounting for the association between HIV-related shame and both emotional and physical well-being, respectively, and loneliness accounting for the association between HIV-related shame and social well-being. HIV-related shame appears to be an important correlate of HRQoL in older PLHIV and may provide a promising leveraging point by which to improve HRQoL in older PLHIV.
本研究调查了与艾滋病毒相关的羞耻感如何与老年艾滋病毒感染者（PLHIV）的健康相关生活质量（HRQoL）相关联。结构方程模型检验了在299名年龄≥50岁的PLHIV样本中，与艾滋病毒相关的羞耻感是否与HRQoL的三个维度（身体、情感和社会福祉）相关联，以及与艾滋病毒相关的羞耻感是否通过抑郁和孤独与三个HRQoL维度存在显著的间接关联。结果表明，抑郁和孤独是关键机制，抑郁至少部分分别解释了与艾滋病毒相关的羞耻感与情感和身体福祉之间的关联，而孤独解释了与艾滋病毒相关的羞耻感与社会福祉之间的关联。与艾滋病毒相关的羞耻感似乎是老年PLHIV中HRQoL的一个重要相关因素，并且可能为改善老年PLHIV的HRQoL提供一个有前景的切入点。
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