Sugimoto K, Minematsu K, Yamaguchi T
Rinsho Shinkeigaku. 1989 May;29(5):574-8.
Presence or absence of aphasic syndrome and its duration were related to the volume of hematoma calculated from CT in 27 consecutive non-surgical cases with left putaminal hemorrhage. In the present study, patients classified into three groups regardless of the types of aphasia; i.e. non-aphasics, transient aphasics and persistent aphasics. Transient aphasics were arbitrarily defined as cases who had presented with more or less evident aphasic syndrome in the acute stage, but almost completely recovered in the chronic stage. Volume of hematoma in non-aphasic patients ranged from 2 to 17 ml, with a mean of 7.7 ml and those in transient cases were from 11 to 23ml with a mean of 17ml. All but one case with persistent aphasia showed the hematoma volume larger than 25ml. This exceptional case was a 83 year-old female who showed marked cortical atrophy on CT. Consequently, the presence of aphasia and its persistence seem to be largely dependent on the size of hematoma in patients with left putaminal hemorrhage. Persistent aphasia may be caused by organic damage of subcortical white matter, when the volume of hematoma exceeds around 25ml.
在27例连续的非手术治疗的左侧壳核出血病例中,失语综合征的有无及其持续时间与根据CT计算的血肿体积有关。在本研究中,无论失语类型如何,患者被分为三组,即非失语患者、短暂性失语患者和持续性失语患者。短暂性失语患者被任意定义为在急性期出现或多或少明显的失语综合征,但在慢性期几乎完全恢复的病例。非失语患者的血肿体积为2至17毫升,平均为7.7毫升,短暂性失语患者的血肿体积为11至23毫升,平均为17毫升。除1例持续性失语患者外,所有持续性失语患者的血肿体积均大于25毫升。这一例外病例是一名83岁女性,CT显示有明显的皮质萎缩。因此,左侧壳核出血患者失语的存在及其持续时间似乎在很大程度上取决于血肿的大小。当血肿体积超过约25毫升时,持续性失语可能由皮质下白质的器质性损伤引起。