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从白及中分离并鉴定出两种新的2-异丁基苹果酸酯。

Isolation and characterization of two new 2-isobutylmalates from Bletilla striata.

作者信息

Guan Huan-Yu, Yan Yan, Wang Yong-Lin, Wang Ai-Min, Liu Jun-Hong, He Xun, Li Yong-Jun, Huang Yong, Liao Shang-Gao

机构信息

Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Ministry of Education, Guiyang 550004, China.

Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China; Guizhou Provincial People's Hospital, Guiyang 550004, China.

出版信息

Chin J Nat Med. 2016 Nov;14(11):871-875. doi: 10.1016/S1875-5364(16)30104-2.

DOI:10.1016/S1875-5364(16)30104-2
PMID:27914531
Abstract

The present study isolated 17 compounds from the tubers of Bletilla striata (Orchidaceae), using various chromatographic techniques. Their structures were identified based on their physical-chemical properties and spectroscopic analyses. Among them, two new 2-isobutylmalates, named bletimalates A (1) and B (2), together with other fifteen known compounds (3-17), were isolated and identified. Additionally, compounds 3, 4, and 8 were isolated from this plant for the first time.

摘要

本研究采用多种色谱技术从白及(兰科)块茎中分离出17种化合物。根据其理化性质和光谱分析确定了它们的结构。其中,分离并鉴定出两种新的2 - 异丁基苹果酸酯,命名为白及苹果酸酯A(1)和B(2),以及其他15种已知化合物(3 - 17)。此外,化合物3、4和8首次从该植物中分离得到。

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