Grecco Marcelle, Santos Viviane Cardoso Dos, Pereira Kaline Medeiros Costa, Andrade Luís Eduardo Coelho, Silva Neusa Pereira da
Universidade Federal de São Paulo (UNIFESP), Departamento de Medicina, Disciplina de Reumatologia, São Paulo, SP, Brazil.
Universidade Federal de São Paulo (UNIFESP), Departamento de Medicina, Disciplina de Reumatologia, São Paulo, SP, Brazil.
Rev Bras Reumatol Engl Ed. 2016 Nov-Dec;56(6):515-520. doi: 10.1016/j.rbre.2016.07.013. Epub 2016 Oct 25.
We evaluated the possible association between FCGR3A V/F (158) polymorphism and SLE susceptibility and clinical phenotype in 305 sequentially retrieved SLE patients and 300 healthy controls from the southeastern part of Brazil by allele-specific polymerase chain reaction. Our results showed no association between FCGR3A 158V/F alleles and susceptibility to SLE in this series of patients albeit the heterozygous genotype was strongly associated with the disease.
