Navarrete-Rodríguez E M, Fernández-Soto J R, Del Rio-Navarro B E, Saucedo-Ramírez O J, Sienra-Monge J J L
Servicio de Alergia e Inmunología Clínica Pediátrica, Hospital Infantil de México Federico Gómez, México, DF, Mexico.
Servicio de Alergia e Inmunología Clínica Pediátrica, Hospital Infantil de México Federico Gómez, México, DF, Mexico.
Allergol Immunopathol (Madr). 2017 Jan-Feb;45(1):11-17. doi: 10.1016/j.aller.2016.09.002. Epub 2016 Nov 30.
House dust mites are a ubiquitous air allergen in the human habitat. It has been shown that exposure to them is a fundamental factor in sensitisation and development of atopic disease. The objective of the study was to analyse changes in sensitisation to Dermatophagoides pteronyssinus (Der p.) in children treated in a tertiary level care hospital in Mexico City for a period of 11 years and compare with other studies carried out in Mexico.
A retrospective study was performed at the Hospital Infantil de México Federico Gómez (HIMFG). Information was gathered from skin tests for Der p. performed in the Allergy Laboratory from January 2004 to April 2015. Patients 2-18 years old who presented for examination of some type of allergic condition and who had immediate hypersensitivity tests to Der p. were included in the study. Results were compared with prior reports from other institutions. Descriptive analysis and χ statistics were used.
A total of 8794 patients were included in the study; 49.3% of the tests (95% CI 48-50) were positive for Der p. The percentage of monosensitised to mites was 2.7% for Der p. (95% CI 2-3). A significant difference was found between the results of older patients and those <6 years old. The frequency of sensitisation had a tendency to decrease during the 11 years analysed in all age groups.
The frequency of sensitisation to Der p. increased with age until reaching adolescence. In the last 11 years a decrease in sensitisation to this air allergen was observed.
屋尘螨是人类居住环境中普遍存在的空气过敏原。研究表明，接触屋尘螨是特应性疾病致敏和发病的一个基本因素。本研究的目的是分析在墨西哥城一家三级护理医院接受治疗的儿童对粉尘螨（Der p.）致敏情况的变化，为期11年，并与在墨西哥进行的其他研究进行比较。
在墨西哥城费德里科·戈麦斯儿童医院（HIMFG）进行了一项回顾性研究。收集了2004年1月至2015年4月在过敏实验室进行的粉尘螨皮肤试验信息。纳入研究的患者年龄在2至18岁之间，因某种过敏状况前来检查，且对粉尘螨进行了速发型超敏反应试验。将结果与其他机构先前的报告进行比较。采用描述性分析和χ统计。
共有8794名患者纳入研究；49.3%的试验（95%可信区间48 - 50）对粉尘螨呈阳性。对螨虫单致敏的比例，粉尘螨为2.7%（95%可信区间2 - 3）。发现老年患者与6岁以下患者的结果存在显著差异。在分析的11年中，所有年龄组的致敏频率都有下降趋势。
对粉尘螨的致敏频率随年龄增长而增加，直至青春期。在过去11年中，观察到对这种空气过敏原的致敏率有所下降。
