Segreti J, Kessler H A, Kapell K, Trenholme G M
Department of Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612.
Diagn Microbiol Infect Dis. 1989 May-Jun;12(3 Suppl):87S-88S. doi: 10.1016/0732-8893(89)90072-2.
The in vitro activity of lomefloxacin (SC 47111 or NY-198), a new quinolone antibiotic, against 11 strains of Chlamydia trachomatis was determined and compared to doxycycline, norfloxacin, and ciprofloxacin. Lomefloxacin had anti-chlamydial activity comparable to that of ciprofloxacin. (MIC and MBC90, 2 micrograms/ml).
测定了新型喹诺酮类抗生素洛美沙星(SC 47111或NY - 198)对11株沙眼衣原体的体外活性,并与强力霉素、诺氟沙星和环丙沙星进行比较。洛美沙星的抗衣原体活性与环丙沙星相当。(MIC和MBC90均为2微克/毫升)