Kheradpir M H
Kinderchirurgische Klinik Kinderspitäler Zürich und Teheran.
Chirurg. 1989 Aug;60(8):541-4.
Between 1939 and 1971 31 cases of sacrococcygeal teratomas were observed at Zurich Children's Hospital, in 5 cases the tumor contained well-developed organs. From 1970 to 1982 25 cases of sacrococcygeal teratomas were identified at Teheran Children's Hospital. In 2 of these cases the tumors were organized. At the same time we observed 2 other cases, one a well differentiated retroperitoneal teratoma, the other an ectopic third leg in the lumbosacral region. In the so-called organized teratomas we found all organs with the exception of heart, lung, kidney, eyes and vertebra. Malignant degeneration was not observed. It is probable that such organized tumors develop from a concentration of rich pluripotent cells at the end of the coccyx. An explanation for ectopic extremities could be the deplacement of pluripotent cells at an early stage of embryonic development.
1939年至1971年间，苏黎世儿童医院共观察到31例骶尾部畸胎瘤，其中5例肿瘤内含有发育良好的器官。1970年至1982年间，德黑兰儿童医院确诊了25例骶尾部畸胎瘤。其中2例肿瘤有组织形成。与此同时，我们还观察到另外2例，1例是高分化腹膜后畸胎瘤，另1例是腰骶部异位第三条腿。在所谓的有组织畸胎瘤中，我们发现了除心脏、肺、肾、眼睛和椎骨以外的所有器官。未观察到恶性变。这种有组织的肿瘤很可能是由尾骨末端丰富的多能细胞聚集发展而来。异位肢体的一种解释可能是多能细胞在胚胎发育早期发生移位。
