Amor-Dorado Juan Carlos, Barreira-Fernandez Maria P, Llorca Javier, Gonzalez-Gay Miguel A
*Otolaryngology Division of Can Misses and Formentera Hospital, Balearic Islands †Otolaryngology Division, Hospital Universitario Lucus Augusti, Lugo ‡Division of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, Santander, CIBER Epidemiología y Salud Pública (CIBERESP) §School of Medicine, University of Cantabria, Santander ||Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain.
Otol Neurotol. 2017 Mar;38(3):448-453. doi: 10.1097/MAO.0000000000001296.
To assess the frequency and characteristics of the oculographic findings and the usefulness of the clinical test of sensory integration and balance (CTSIB) for the evaluation of balance in patients with psoriatic arthritis (PsA) by comparing this test with the computerized dynamic posturography (CDP).
A series of consecutive patients that fulfilled the Moll and Wright criteria for PsA and matched controls were studied.
The study was performed at the Otolaryngology Division of a tertiary reference center.
Vestibular evaluation including CTSIB followed by CDP was performed to all patients and age, sex, and ethnically frequency-matched controls.
Patterns of CTSIB and CDP (gold standard) were assessed and compared.
Sixty PsA patients (63.3% women) and 60 matched controls.
PsA patients had higher frequency of abnormal oculocephalic response (13.3%) and abnormal caloric test (26.7%) than controls (0% in both cases) (p = 0.006 and p < 0.001, respectively). Benign paroxysmal positional vertigo (BPPV) was diagnosed in two (3.4%) patients and none of the controls (p = 1). Significantly increased frequency of abnormal CTSIB test with vestibular loss pattern (33.3%) in patients compared with controls (6%) was observed (p = 0.002). Significantly increased frequency of abnormal CDP was also observed in PsA patients (14 [23.3%] versus 0 [0%] of controls) (p < 0.001). CTSIB yielded 100% sensitivity, 73% specificity, 48% positive predictive value, and 100% negative predictive value.
This study indicates that oculographic findings are common in PsA. CTSIB is useful for assessing balance disorder screening in the routine clinical practice in these patients.
通过将感觉统合与平衡临床测试（CTSIB）与计算机化动态姿势描记法（CDP）进行比较，评估银屑病关节炎（PsA）患者眼动图检查结果的频率和特征以及CTSIB对评估平衡功能的实用性。
对一系列符合Moll和Wright PsA标准的连续患者及匹配的对照组进行研究。
研究在一家三级参考中心的耳鼻喉科进行。
对所有患者及年龄、性别和种族频率匹配的对照组进行包括CTSIB及随后的CDP在内的前庭评估。
评估并比较CTSIB和CDP（金标准）的模式。
60例PsA患者（63.3%为女性）和60例匹配的对照组。
PsA患者的眼头反射异常（13.3%）和冷热试验异常（26.7%）的频率高于对照组（两者均为0%）（p分别为0.006和p<0.001）。两名（3.4%）患者被诊断为良性阵发性位置性眩晕（BPPV），而对照组无一例（p = 1）。观察到患者中前庭丧失模式的CTSIB测试异常频率（33.3%）与对照组（6%）相比显著增加（p = 0.002）。PsA患者中CDP异常频率也显著增加（14例[23.3%]对对照组0例[0%]）（p<0.001）。CTSIB的敏感性为100%，特异性为73%，阳性预测值为48%，阴性预测值为100%。
本研究表明眼动图检查结果在PsA中很常见。CTSIB有助于在这些患者的常规临床实践中评估平衡障碍筛查。
