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Improving on effective antiretroviral therapy: how good will a cure have to be?

作者信息

Freedberg Kenneth A, Sax Paul E

机构信息

Medical Practice Evaluation Center and Divisions of General Internal Medicine and Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

出版信息

J Med Ethics. 2017 Feb;43(2):71-73. doi: 10.1136/medethics-2016-103907. Epub 2016 Dec 5.

DOI:10.1136/medethics-2016-103907
PMID:27920163
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5269517/
Abstract
摘要

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本文引用的文献

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Introduction to the Special Issue on "The World Health Organization Choosing Interventions That Are Cost-Effective (WHO-CHOICE) Update".关于“世界卫生组织选择具有成本效益的干预措施(WHO-CHOICE)更新”特刊的介绍。
Int J Health Policy Manag. 2021 Nov 1;10(11):670-672. doi: 10.34172/ijhpm.2021.105.
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Cost-Effectiveness of Frequent HIV Testing of High-Risk Populations in the United States.美国高危人群频繁进行艾滋病毒检测的成本效益分析
J Acquir Immune Defic Syndr. 2016 Mar 1;71(3):323-30. doi: 10.1097/QAI.0000000000000838.
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HIV cure strategies: how good must they be to improve on current antiretroviral therapy?艾滋病病毒治愈策略:为超越当前的抗逆转录病毒疗法,这些策略必须达到何种效果?
PLoS One. 2014 Nov 14;9(11):e113031. doi: 10.1371/journal.pone.0113031. eCollection 2014.
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PLoS One. 2014 Oct 7;9(10):e109148. doi: 10.1371/journal.pone.0109148. eCollection 2014.
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Updating cost-effectiveness--the curious resilience of the $50,000-per-QALY threshold.更新成本效益——每质量调整生命年5万美元阈值令人好奇的韧性。
N Engl J Med. 2014 Aug 28;371(9):796-7. doi: 10.1056/NEJMp1405158.
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Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV.对感染 HIV 人群的自体 CD4 T 细胞中的 CCR5 进行基因编辑。
N Engl J Med. 2014 Mar 6;370(10):901-10. doi: 10.1056/NEJMoa1300662.
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Cost-effectiveness of HIV treatment as prevention in serodiscordant couples.艾滋病毒治疗预防血清学不一致的性伴侣间传播的成本效益。
N Engl J Med. 2013 Oct 31;369(18):1715-25. doi: 10.1056/NEJMsa1214720.
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Mortality in well controlled HIV in the continuous antiretroviral therapy arms of the SMART and ESPRIT trials compared with the general population.在 SMART 和 ESPRIT 试验的连续抗逆转录病毒治疗组中,经过良好控制的 HIV 患者的死亡率与普通人群相比。
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Blood. 2011 Mar 10;117(10):2791-9. doi: 10.1182/blood-2010-09-309591. Epub 2010 Dec 8.