2016年的显著进展。 - Suppr

Notable advances 2016.

作者信息

Stower Hannah, Bondar Tanya, Farrell Alison, Basson Michael, Levinson Randy, Borowski Christine, Carmona Javier, Benedetti Brett

出版信息

Nat Med. 2016 Dec 6;22(12):1374-1376. doi: 10.1038/nm1216-1374.

DOI:10.1038/nm1216-1374

PMID:27923031

Abstract

摘要

相似文献

Notable advances 2016.

Nat Med. 2016 Dec 6;22(12):1374-1376. doi: 10.1038/nm1216-1374.

Genomic engineering and the future of medicine.

JAMA. 2015 Feb 24;313(8):791-2. doi: 10.1001/jama.2015.287.

Genome editing for dissecting and curing human genetic diseases.

J Hum Genet. 2018 Feb;63(2):105. doi: 10.1038/s10038-017-0380-0. Epub 2018 Jan 25.

Mini enzyme moves gene editing closer to the clinic.

Nature. 2015 Apr 2;520(7545):18. doi: 10.1038/520018a.

Engineering the immune system to cure genetic diseases, HIV, and cancer.

Curr Opin Immunol. 2012 Oct;24(5):576-9. doi: 10.1016/j.coi.2012.09.004.

Gene therapy matures in the clinic.

Nat Biotechnol. 2012 Jul 10;30(7):588-93. doi: 10.1038/nbt.2290.

[The CRISPR system can correct or modify the expression of genes responsible for hereditary diseases].

Med Sci (Paris). 2015 Nov;31(11):1014-22. doi: 10.1051/medsci/20153111016. Epub 2015 Nov 17.

CRISPR/Cas9 system: a powerful technology for in vivo and ex vivo gene therapy.

Sci China Life Sci. 2017 May;60(5):468-475. doi: 10.1007/s11427-017-9057-2. Epub 2017 Apr 20.

Molecular medicine: a primer for clinicians--part IX human gene therapy.

S D J Med. 1996 Feb;49(2):55-60.

CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseases.

Oncotarget. 2016 Aug 9;7(32):52541-52552. doi: 10.18632/oncotarget.9646.

本文引用的文献

Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors.

Cell. 2016 Oct 6;167(2):419-432.e16. doi: 10.1016/j.cell.2016.09.011. Epub 2016 Sep 29.

Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice.

Cell. 2016 Sep 8;166(6):1445-1458.e12. doi: 10.1016/j.cell.2016.07.030.

Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis.

Nature. 2016 Aug 11;536(7615):215-8. doi: 10.1038/nature19076. Epub 2016 Aug 3.

Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease.

Science. 2016 Jul 8;353(6295):179-84. doi: 10.1126/science.aaf6756. Epub 2016 Jun 30.

Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors.

Nature. 2016 Jun 2;534(7605):129-32. doi: 10.1038/nature17960. Epub 2016 May 25.

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.

Cell. 2016 May 5;165(4):921-35. doi: 10.1016/j.cell.2016.04.001. Epub 2016 Apr 21.

Complement and microglia mediate early synapse loss in Alzheimer mouse models.

Science. 2016 May 6;352(6286):712-716. doi: 10.1126/science.aad8373. Epub 2016 Mar 31.

Lens regeneration using endogenous stem cells with gain of visual function.

Nature. 2016 Mar 17;531(7594):323-8. doi: 10.1038/nature17181. Epub 2016 Mar 9.

Expanding antigen-specific regulatory networks to treat autoimmunity.

Nature. 2016 Feb 25;530(7591):434-40. doi: 10.1038/nature16962. Epub 2016 Feb 17.

Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits.

Cell. 2016 Feb 11;164(4):770-9. doi: 10.1016/j.cell.2016.01.011. Epub 2016 Jan 28.

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相似文献

Notable advances 2016.

Nat Med. 2016 Dec 6;22(12):1374-1376. doi: 10.1038/nm1216-1374.

Genomic engineering and the future of medicine.

JAMA. 2015 Feb 24;313(8):791-2. doi: 10.1001/jama.2015.287.

Genome editing for dissecting and curing human genetic diseases.

J Hum Genet. 2018 Feb;63(2):105. doi: 10.1038/s10038-017-0380-0. Epub 2018 Jan 25.

Mini enzyme moves gene editing closer to the clinic.

Nature. 2015 Apr 2;520(7545):18. doi: 10.1038/520018a.

Engineering the immune system to cure genetic diseases, HIV, and cancer.

Curr Opin Immunol. 2012 Oct;24(5):576-9. doi: 10.1016/j.coi.2012.09.004.

Gene therapy matures in the clinic.

Nat Biotechnol. 2012 Jul 10;30(7):588-93. doi: 10.1038/nbt.2290.

[The CRISPR system can correct or modify the expression of genes responsible for hereditary diseases].

Med Sci (Paris). 2015 Nov;31(11):1014-22. doi: 10.1051/medsci/20153111016. Epub 2015 Nov 17.

CRISPR/Cas9 system: a powerful technology for in vivo and ex vivo gene therapy.

Sci China Life Sci. 2017 May;60(5):468-475. doi: 10.1007/s11427-017-9057-2. Epub 2017 Apr 20.

Molecular medicine: a primer for clinicians--part IX human gene therapy.

S D J Med. 1996 Feb;49(2):55-60.

CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseases.

Oncotarget. 2016 Aug 9;7(32):52541-52552. doi: 10.18632/oncotarget.9646.

本文引用的文献

Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors.

Cell. 2016 Oct 6;167(2):419-432.e16. doi: 10.1016/j.cell.2016.09.011. Epub 2016 Sep 29.

Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice.

Cell. 2016 Sep 8;166(6):1445-1458.e12. doi: 10.1016/j.cell.2016.07.030.

Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis.

Nature. 2016 Aug 11;536(7615):215-8. doi: 10.1038/nature19076. Epub 2016 Aug 3.

Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease.

Science. 2016 Jul 8;353(6295):179-84. doi: 10.1126/science.aaf6756. Epub 2016 Jun 30.

Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors.

Nature. 2016 Jun 2;534(7605):129-32. doi: 10.1038/nature17960. Epub 2016 May 25.

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.

Cell. 2016 May 5;165(4):921-35. doi: 10.1016/j.cell.2016.04.001. Epub 2016 Apr 21.

Complement and microglia mediate early synapse loss in Alzheimer mouse models.

Science. 2016 May 6;352(6286):712-716. doi: 10.1126/science.aad8373. Epub 2016 Mar 31.

Lens regeneration using endogenous stem cells with gain of visual function.

Nature. 2016 Mar 17;531(7594):323-8. doi: 10.1038/nature17181. Epub 2016 Mar 9.

Expanding antigen-specific regulatory networks to treat autoimmunity.

Nature. 2016 Feb 25;530(7591):434-40. doi: 10.1038/nature16962. Epub 2016 Feb 17.

Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits.

Cell. 2016 Feb 11;164(4):770-9. doi: 10.1016/j.cell.2016.01.011. Epub 2016 Jan 28.

Notable advances 2016.

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