Primus R J, Kellogg C K
Department of Psychology, University of Rochester, New York.
Dev Psychobiol. 1989 Sep;22(6):633-43. doi: 10.1002/dev.420220608.
The influence of pubertal age on the differential effect of a familiar versus an unfamiliar environment on social interaction (SI) in pairs of male rats was evaluated. The decrease in SI induced by the unfamiliar environment in adult rats is considered an anxiety-related response. Intact male rats and male rats castrated at 19 days were tested for SI at 28, 35, and 60 days of age. The results revealed that in the intact rats, decreased SI in an unfamiliar environment was evident at 35 and 60 days but not at 28 days. The behavioral composition of the environment-induced response at 35 days was different from that measured at 60 days. Prepubertal castration prevented the decrease in SI in the unfamiliar environment at both 35 and 60 days. This study demonstrated the emergence with the onset of puberty of a specific behavioral response to an anxiogenic condition. Furthermore, the development of this environment-related behavioral response was influenced by gonadal secretion(s), suggesting the importance of gonadal function to the emergence of this response.
评估了青春期年龄对雄性大鼠成对饲养时，熟悉环境与陌生环境对社交互动（SI）的差异影响。成年大鼠在陌生环境中诱导的社交互动减少被认为是一种与焦虑相关的反应。对完整雄性大鼠和19日龄阉割的雄性大鼠在28、35和60日龄时进行社交互动测试。结果显示，在完整大鼠中，陌生环境中社交互动减少在35和60日龄时明显，但在28日龄时不明显。35日龄时环境诱导反应的行为组成与60日龄时测量的不同。青春期前阉割可防止35和60日龄时陌生环境中社交互动的减少。本研究证明了青春期开始时出现了对焦虑源条件的特定行为反应。此外，这种与环境相关的行为反应的发展受性腺分泌的影响，表明性腺功能对这种反应的出现很重要。
