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[肺坏疽的发病机制与治疗的若干问题]

[Several problems of pathogenesis and treatment of pulmonary gangrene].

作者信息

Lesnitskiĭ L S, Kostiuchenko A L, Tulupov A N

出版信息

Grudn Khir. 1989 Jul-Aug(4):39-44.

PMID:2792876
Abstract

The pathology and clinical picture of gangrene of the lungs were studied in detail in 213 patients in the specialized surgical department of the clinic of hospital surgery of the Kirov Military-Medical Academy from 1969 to 1987. The diffuse from of the disease (DLG) was encountered in 111 patients and the localized form (LLG) in 102 patients. The indications for various methods of treatment of lung gangrene are formulated. Lung resection was performed most frequently (in 67% of patients). Intensive preoperative therapy including hyperbaric oxygenation is necessary for most patients with gangrene of the lungs. Total mortality was 39.6% among patients with DLG and 16.6% among those with LLG. Mortality among patients with DLG after resection of the lungs was 34.1%. Study of the late-term results showed that 130 (61%) patients were alive, 64 (30%) had died from the main disease and its complications and 7 (3.5%) from other causes, the fate of 12 (5.7%) persons was not known.

摘要

1969年至1987年期间,在基洛夫军事医学院医院外科诊所的专科外科对213例肺坏疽患者的病理和临床情况进行了详细研究。111例患者出现弥漫性疾病形式(DLG),102例患者出现局限性形式(LLG)。制定了肺坏疽各种治疗方法的适应证。肺切除术最为常用(67%的患者)。对于大多数肺坏疽患者,包括高压氧疗在内的强化术前治疗是必要的。DLG患者的总死亡率为39.6%,LLG患者的总死亡率为16.6%。DLG患者肺切除术后的死亡率为34.1%。对远期结果的研究表明,130例(61%)患者存活,64例(30%)死于主要疾病及其并发症,7例(3.5%)死于其他原因,12例(5.7%)患者的命运不明。

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