Spirtos N M, Doshi B P, Kapp D S, Teng N
Department of Gynecology and Obstetrics, Stanford University Medical Center, California 94305.
Gynecol Oncol. 1989 Oct;35(1):20-6. doi: 10.1016/0090-8258(89)90004-8.
A retrospective analysis of 38 patients with primary squamous cell carcinoma of the vagina seen at Stanford University Medical Center from 1958 to 1984 was undertaken. Patients were analyzed with regard to symptoms, stage, treatment techniques, survival, patterns of failure, and complications. Eighteen patients were classified as FIGO Stage I, 5 as Stage II, 10 as Stage III, and 5 as Stage IV. The 5-year disease-free survival was 94% in Stage I, 80% in Stage II, 50% in Stage III, and 0% in Stage IV. Five patients (13%) had eight major complications secondary to treatment. Only 2 of 23 patients with Stage I or Stage II disease developed a recurrence. There was a significant correlation between dose and response in patients treated with radiotherapy.
对1958年至1984年间在斯坦福大学医学中心就诊的38例原发性阴道鳞状细胞癌患者进行了回顾性分析。对患者的症状、分期、治疗技术、生存率、失败模式和并发症进行了分析。18例患者被归类为国际妇产科联盟（FIGO）I期，5例为II期，10例为III期，5例为IV期。I期患者的5年无病生存率为94%，II期为80%，III期为50%，IV期为0%。5例患者（13%）出现了8例继发于治疗的严重并发症。23例I期或II期疾病患者中只有2例复发。接受放射治疗的患者中，剂量与反应之间存在显著相关性。
