Ostergaard G Z, Jacobsen B B
Department of Paediatrics, Roskilde Hospital, Denmark.
Horm Res. 1989;31(4):190-2. doi: 10.1159/000181114.
Autoimmune thyroiditis in infancy is a very rare condition. Only 1 case has been reported previously. In the present patient an acquired primary hypothyroidism with high titers of thyroid microsomal antibodies was diagnosed at the age of 7 months. The patient died at 9 months of age in a sepsis-like condition. Autopsy revealed an atrophic thyroiditis. The more severe and complex clinical picture of autoimmune thyroiditis in infancy compared to that later in childhood is discussed.
婴儿期自身免疫性甲状腺炎是一种非常罕见的病症。此前仅报道过1例。在本病例中,一名7个月大的婴儿被诊断为获得性原发性甲状腺功能减退症,甲状腺微粒体抗体滴度很高。该患儿在9个月大时死于类似败血症的病症。尸检显示为萎缩性甲状腺炎。本文讨论了婴儿期自身免疫性甲状腺炎与儿童期后期相比更为严重和复杂的临床表现。