Huang Jianrong, Song Leming, Xie Donghua, Li Monong, Deng Xiaolin, Hu Min, Peng Zuofeng, Liu Tairong, Du Chuance, Yao Lei, Liu Shengfeng, Guo Shulin, Zhong Jiuqing
Department of Urology, The Affiliated Ganzhou Hospital of Nanchang University, 17 Hongqi Avenue, Ganzhou, Jiangxi, 341000, China.
Department of Urology, Detroit Medical Center, Detroit, MI, 48201, USA.
BMC Urol. 2016 Dec 8;16(1):71. doi: 10.1186/s12894-016-0184-0.
Calculus pyonephrosis is difficult to manage. The aim of this study is to explore the value of a patented suctioning sheath assisted minimally invasive percutaneous nephrolithotomy (MPCNL) in the treatment of calculus pyonephrosis.
One hundred and eighty two patients with calculus pyonephrosis were randomizely divided into observation group (n = 91) and control group (n = 91). The control group was treated with MPCNL traditionally using peel-away sheath while the observation group was treated with MPCNL using the patented suctioning sheath.
All the patients in the observation group underwent one stage surgical treatment, 14 patients in the control group underwent first-stage surgery with the rest of the group underwent one stage surgery. The complication rate was 12.1% in the observation group, significantly lower than the rate in the control group which was 51.6%; One surgery stone clearance in the observation group was 96.7% while it was 73.6% in the control group; operative time in the observation group was (54.5 ± 14.5) min, compared to (70.2 ± 11.7) min in the control group; the bleeding amount in the observation group was (126.4 ± 47.2) ml, compared to (321.6 ± 82.5) ml in the control group; the hospitalization duration for the observation group was (6.4 ± 2.3) days, compared to (10.6 ± 3.7) days in the control group. Comparison of the above indicators, the observation group was better than the control group with significant difference (p < 0.001 each).
Minimally invasive percutaneous nephrolithotomy with the aid of the patented suctioning sheath in the treatment of calculus pyonephrosis in one surgery is economic, practical, and warrants clinical promotion.
This study was registered with Chinese Clinical Trial Registry on May 18, 2016 (retrospective registration) with a trial registration number of ChiCTR-IOR-16008490 .
脓性肾积石的治疗颇具难度。本研究旨在探讨一种专利吸引鞘辅助微创经皮肾镜取石术（MPCNL）在脓性肾积石治疗中的价值。
182例脓性肾积石患者被随机分为观察组（n = 91）和对照组（n = 91）。对照组采用传统的带 Peel-away 鞘的 MPCNL 治疗，而观察组采用专利吸引鞘进行 MPCNL 治疗。
观察组所有患者均接受一期手术治疗，对照组14例患者接受一期手术，其余患者接受二期手术。观察组并发症发生率为12.1%，显著低于对照组的51.6%；观察组一期手术结石清除率为96.7%，而对照组为73.6%；观察组手术时间为（54.5 ± 14.5）分钟，对照组为（70.2 ± 11.7）分钟；观察组出血量为（126.4 ± 47.2）毫升，对照组为（321.6 ± 82.5）毫升；观察组住院时间为（6.4 ± 2.3）天，对照组为（10.6 ± 3.7）天。上述指标比较，观察组均优于对照组，差异有统计学意义（各 p < 0.001）。
专利吸引鞘辅助微创经皮肾镜取石术治疗脓性肾积石一期手术经济、实用，值得临床推广。
本研究于2016年5月18日在中国临床试验注册中心注册（回顾性注册），试验注册号为 ChiCTR-IOR-16008490 。
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