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迷你肾镜联合压力吸引:治疗尿路感染患者肾内结石的经皮肾镜碎石取石术的有效工具

Mini-nephroscope combined with pressure suction: an effective tool in MPCNL for intrarenal stones in patients with urinary tract infections.

作者信息

Xu Guibin, He Yongzhong, Zhao Haibo, Jiang Xianhan, Feng Gang, Yang Weiqing, Xu Wei, Xie Qingling, Li Xun

机构信息

Department of Urology, Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.

Center for Minimally Invasive Technique Innovation and Translation, Guangzhou Medical University, Guangzhou, 510700, China.

出版信息

Urolithiasis. 2016 Oct;44(5):445-50. doi: 10.1007/s00240-016-0859-8. Epub 2016 Feb 9.

Abstract

We report our experience with a mini-nephroscope connected to pressure suction as a modified minimally invasive percutaneous nephrolithotomy (MPCNL) technique to manage intrarenal stones in patients with a urinary tract infection (UTI). We used a mini-nephroscope connected to pressure suction to aspirate infected urine and reduce intrapelvic pressure. From January 2010 to June 2014, we treated 683 patients with intrarenal stones and UTI with this modified MPCNL technique in our department (Group A). Patients with an intrarenal stone and without UTI treated by this modified MPCNL (Group B, N = 422) and patients with an intrarenal stone and UTI but treated by traditional MCPNL without pressure suction (Group C, N = 95) were collected as control groups. In group A, 635 of the 683 patients (93 %) had a positive urine culture preoperatively and the other 48 patients (7 %) were diagnosed with pyonephrosis intraoperatively. The mean stone bulk was 843 ± 151.4 mm(2) and mean operative time was 71.0 ± 11.5 min. The mean stone bulk and operative time were similar to those of group B and group C. However, the rates of infectious complications for groups A (6.4 %) and B (4.9 %) were similar, but higher in group C (28.4 %). In group A, only 38 patients had fever and 6 patients developed sepsis. None of the patients showed progression to multiple organ dysfunction syndrome or died in all of patients. Our results demonstrated that this modified MPCNL technique is safe, feasible, and efficient for managing intrarenal calculi in patients with an UTI.

摘要

我们报告了使用连接压力吸引装置的微型肾镜作为改良的微创经皮肾镜取石术(MPCNL)技术来处理尿路感染(UTI)患者肾内结石的经验。我们使用连接压力吸引装置的微型肾镜抽吸感染尿液并降低肾盂内压力。2010年1月至2014年6月,我们科室采用这种改良的MPCNL技术治疗了683例肾内结石合并UTI的患者(A组)。收集采用这种改良MPCNL治疗的无UTI的肾内结石患者(B组,n = 422)以及有肾内结石合并UTI但采用传统无压力吸引的MPCNL治疗的患者(C组,n = 95)作为对照组。A组683例患者中,635例(93%)术前尿培养阳性,另外48例(7%)术中诊断为肾积脓。结石平均体积为843±151.4 mm²,平均手术时间为71.0±11.5分钟。平均结石体积和手术时间与B组和C组相似。然而,A组(6.4%)和B组(4.9%)的感染并发症发生率相似,但C组(28.4%)更高。A组中,仅38例患者发热,6例患者发生脓毒症。所有患者均未进展为多器官功能障碍综合征或死亡。我们的结果表明,这种改良的MPCNL技术对于处理UTI患者的肾内结石是安全、可行且有效的。

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