Kurt A M, Unni K K, Sim F H, McLeod R A
Department of Orthopedics, Mayo Clinic, Rochester, MN 55905.
Hum Pathol. 1989 Oct;20(10):965-76. doi: 10.1016/0046-8177(89)90268-2.
Chondroblastomas are unusual benign lesions of bone. They classically occur at the ends of long bones in young persons. The roentgenographic and histologic features are typical. We had an opportunity to study a large number of chondroblastomas. Most of the cases came from the consultation file started by Dr D. C. Dahlin at the Mayo Clinic. This method of ascertainment may tend to load our series with unusual and atypical examples. We found some unusual locations, such as the skull and facial bones and the small tubular bones of the hands and feet. We also found some unusual histologic features, such as mitotic activity, necrosis, and cellular atypia. However, despite the unusual features, the biological behavior of these tumors was that of a benign process with only limited local aggressiveness.
软骨母细胞瘤是一种罕见的骨良性病变。典型情况下，它们发生在年轻人长骨的末端。其X线和组织学特征具有典型性。我们有机会研究大量软骨母细胞瘤。大多数病例来自梅奥诊所的D.C.达林医生建立的会诊档案。这种确诊方法可能会使我们的病例系列中出现异常和非典型的例子。我们发现了一些不寻常的部位，如颅骨、面骨以及手足的小管状骨。我们还发现了一些不寻常的组织学特征，如有丝分裂活性、坏死和细胞异型性。然而，尽管有这些不寻常的特征，这些肿瘤的生物学行为仍表现为良性过程，仅具有有限的局部侵袭性。
