Elbahri Hassan Mohammed Hassan, AbdElmaged Hozifa Mohammed Ali, Awad Musa Yassin Mohamed, Yousif Yousif Omer Elgaili, Khalafalla Sara Gamareldein A
Department of Surgery, College of Medicine and Health Sciences, Arabian Gulf University (AGU), Bahrain.
Faculty of Medicine, International University of Africa (IUA), Khartoum, Sudan.
Ann Med Surg (Lond). 2025 Mar 28;87(5):2626-2632. doi: 10.1097/MS9.0000000000003191. eCollection 2025 May.
Chondroblastoma is a rare, benign neoplasm accounting for less than 1% of all primary bone tumors. It is treated with complete surgical curettage with or without chemical or physical adjuvants. The present study aims to assess the functional and oncological outcomes of patients with chondroblastoma treated with intralesional curettage supplemented by bone cementation of the resulting bone defect.
This study is an observational, descriptive, prospective hospital-based study conducted from April 2022 to August 2022 at the Ibrahim Malik Teaching Hospital and Future Hospital in Khartoum State, Sudan. It included patients with chondroblastoma who were treated with intralesional curettage and subsequent filling of the remaining bone cavity with bone cement. The researchers collected data from the patients' hospital records, as well as with the aid of the Musculoskeletal Tumor Society Scoring System, and analyzed them using SPSS V 28.
The study population comprised 32 patients with a mean age of 20 ± 6 years; the majority were males, 62.5% ( = 20), and students by occupation, 66% ( = 21). The proximal tibia was the most commonly involved site, corresponding to 59% of the cases ( = 19). Functional evaluation using the Musculoskeletal Tumor Society Scoring System revealed a statistically significant improvement from a preoperative score of 62 ± 10 to a postoperative score of 91 ± 3 ( value = 0.001). No recurrence or need for amputation was reported. Almost half of the study participants, 47% ( = 15) experienced moderate to severe pain. Postoperatively, 97% ( = 31) were satisfied with pain relief, and all patients were satisfied with the procedure. Functional outcomes improve with time after surgery.
The study showed a favorable outcome regarding pain relief and functional restoration in patients with chondroblastoma. The oncological results were also satisfactory; no recurrence, or need for amputation was recorded.
软骨母细胞瘤是一种罕见的良性肿瘤，占所有原发性骨肿瘤的比例不到1%。其治疗方法为完整的手术刮除术，可辅以或不辅以化学或物理辅助剂。本研究旨在评估采用病灶内刮除术并辅以骨水泥填充所形成的骨缺损治疗软骨母细胞瘤患者的功能和肿瘤学结局。
本研究是一项于2022年4月至2022年8月在苏丹喀土穆州易卜拉欣·马利克教学医院和未来医院进行的基于医院的观察性、描述性、前瞻性研究。研究对象为接受病灶内刮除术并随后用骨水泥填充剩余骨腔的软骨母细胞瘤患者。研究人员从患者的医院记录中收集数据，并借助肌肉骨骼肿瘤学会评分系统进行收集，然后使用SPSS V 28进行分析。
研究人群包括32例患者，平均年龄为20±6岁；大多数为男性，占62.5%（n = 20），职业为学生的占66%（n = 21）。胫骨近端是最常受累的部位，占病例的59%（n = 19）。使用肌肉骨骼肿瘤学会评分系统进行的功能评估显示，术前评分为62±10，术后评分为91±3，差异有统计学意义（P值 = 0.001）。未报告复发或截肢需求。近一半的研究参与者，即47%（n = 15）经历了中度至重度疼痛。术后，97%（n = 31）对疼痛缓解感到满意，所有患者对手术都感到满意。功能结局在术后随时间改善。
该研究表明软骨母细胞瘤患者在疼痛缓解和功能恢复方面有良好的结局。肿瘤学结果也令人满意；未记录到复发或截肢需求。
