Köckerling F, Bittner R, Kuthe A, Stechemesser B, Lorenz R, Koch A, Reinpold W, Niebuhr H, Hukauf M, Schug-Pass C
Department of Surgery and Center for Minimally Invasive Surgery, Academic Teaching Hospital of Charité Medical School, Vivantes Hospital, Neue Bergstrasse 6, 13585, Berlin, Germany.
Hernia Center, Winghofer Medicum, Winghofer Strasse 42, 72108, Rottenburg am Neckar, Germany.
Surg Endosc. 2017 Aug;31(8):3168-3185. doi: 10.1007/s00464-016-5342-7. Epub 2016 Dec 8.
On the basis of six meta-analyses, the guidelines of the European Hernia Society (EHS) recommend laparo-endoscopic recurrent repair following previous open inguinal hernia operation and, likewise, open repair following previous laparo-endoscopic operation. So far no data are available on implementation of the guidelines or for comparison of outcomes. Besides, there are no studies for comparison of outcomes for compliance versus non-compliance with the guidelines.
In total, 4812 patients with elective unilateral recurrent inguinal hernia repair in men were enrolled between September 1, 2009, and September 17, 2014, in the Herniamed Registry. Only patients with 1-year follow-up were included.
Out of the 2482 laparo-endoscopic recurrent repair operations 90.5% of patients, and out of the 2330 open recurrent repair procedures only 38.5% of patients, were operated on in accordance with the guidelines of the EHS. Besides, on compliance with the guidelines multivariable analysis demonstrated for laparo-endoscopic recurrent repair a significantly lower risk of pain at rest (OR 0.643 [0.476; 0.868]; p = 0.004) and pain on exertion (OR 0.679 [0.537; 0.857]; p = 0.001). Comparison of laparo-endoscopic and open recurrent repair in settings of compliance versus non-compliance with the guidelines showed a higher incidence of perioperative complications and re-recurrences for recurrent repairs that did not comply with the guidelines.
The EHS guidelines for recurrent inguinal hernia repair are not yet being observed to the extent required. Non-compliance with the guidelines is associated with higher perioperative complication rates and higher risk of re-recurrence. Even on compliance with the guidelines, the risk of pain at rest and pain on exertion is higher after open recurrent repair than after laparo-endoscopic repair.
基于六项荟萃分析,欧洲疝学会(EHS)指南建议,对于既往有开放性腹股沟疝手术史的患者采用腹腔镜 - 内镜下复发性修补术,同样,对于既往有腹腔镜 - 内镜手术史的患者采用开放性修补术。到目前为止,尚无关于指南实施情况或结果比较的数据。此外,也没有关于遵循与不遵循指南的结果比较的研究。
2009年9月1日至2014年9月17日期间,共有4812例择期进行单侧复发性腹股沟疝修补术的男性患者被纳入疝病登记系统。仅纳入有1年随访的患者。
在2482例腹腔镜 - 内镜下复发性修补手术中,90.5%的患者按照EHS指南进行手术;而在2330例开放性复发性修补手术中,只有38.5%的患者按照指南进行手术。此外,多变量分析表明,对于腹腔镜 - 内镜下复发性修补术,遵循指南的患者静息时疼痛风险显著降低(比值比[OR]0.643[0.476;0.868];p = 0.004)以及用力时疼痛风险显著降低(OR 0.679[0.537;0.857];p = 0.001)。在遵循与不遵循指南的情况下,对腹腔镜 - 内镜下与开放性复发性修补术进行比较,结果显示未遵循指南的复发性修补术围手术期并发症和再次复发的发生率更高。
EHS复发性腹股沟疝修补术指南尚未得到充分遵循。不遵循指南与更高的围手术期并发症发生率和更高的再次复发风险相关。即使遵循指南,开放性复发性修补术后静息时疼痛和用力时疼痛的风险也高于腹腔镜 - 内镜下修补术后。