Department of Chemistry, Zhejiang Sci-Tech University , Xiasha West Higher Education District, Hangzhou, 310018, China.
Org Lett. 2016 Dec 2;18(23):6168-6171. doi: 10.1021/acs.orglett.6b03179. Epub 2016 Nov 16.
A facile rhodium-catalyzed transannulation of 1-sulfonyl-1,2,3-triazoles with β-diketones was realized, and a series of multisubstituted 2-carbonylpyrroles were synthesized efficiently (up to 94% yield). The protocol features several advantages, such as readily available materials, mild reaction conditions, a concise operating procedure, a broad reaction scope, and excellent regioselectivity when benzoylacetone derivatives were used.
一种简便的铑催化 1-磺酰基-1,2,3-三唑与β-二酮的跨环反应被实现，高效地合成了一系列多取代的 2-羰基吡咯（高达 94%的产率）。该方案具有几个优点，如易得的原料、温和的反应条件、简洁的操作步骤、广泛的反应范围，以及当使用苯甲酰丙酮衍生物时优异的区域选择性。
