Department of Psychiatry and Behavioral Neurosciences, University of Cincinnati College of Medicine, Cincinnati, OH, USA. E-mail:
Department of Veterans Affairs Medical Center, Cincinnati, OH, USA.
Cleve Clin J Med. 2016 Dec;83(12):895-904. doi: 10.3949/ccjm.83a.15050.
Taurine is an amino acid found abundantly in brain, retina, heart, and reproductive organ cells, as well as in meat and seafood. But it is also a major ingredient in popular "energy drinks," which thus constitute a major source of taurine supplementation. Unfortunately, little is known about taurine's neuroendocrine effects. The authors review the sparse data and provide a basic background on the structure, synthesis, distribution, metabolism, mechanisms, effects, safety, and currently proposed therapeutic targets of taurine.
牛磺酸是一种在大脑、视网膜、心脏和生殖器官细胞以及肉类和海鲜中含量丰富的氨基酸。但它也是流行的“能量饮料”的主要成分,因此成为牛磺酸补充的主要来源。不幸的是,人们对牛磺酸的神经内分泌作用知之甚少。作者回顾了稀少的数据,并提供了关于牛磺酸的结构、合成、分布、代谢、机制、作用、安全性以及目前提出的治疗靶点的基本背景。