Kalhor Neda, Weissferdt Annikka, Moran Cesar A
Department of Pathology, The University of Texas, MD Anderson Cancer Center, Houston, TX.
Adv Anat Pathol. 2017 Jan;24(1):15-23. doi: 10.1097/PAP.0000000000000132.
The existence of primary salivary gland type tumors (SGTs), similar to those occurring in the major salivary glands, is well known in the thoracic cavity. When they occur in this anatomic area, these tumors more commonly arise from the lung. However, the existence of these tumors primarily affecting the thymus, although recognized in the literature, is rather not well documented or known. In addition, contrary to the primary lung SGTs, which are predominantly of the malignant type, these tumors when occur in thymus encompass a wider spectrum of biology ranging from benign to low grade, and high grade malignancy. The recognition of SGTs in the thymus, even though rare, is important to properly address treatment and prognosis. Herein, we will discuss the numerous benign a malignant SGTs that have been described in the thymus and highlight the difficulty that these tumors may pose when occurring in the thymic area.
原发性涎腺型肿瘤(SGTs)的存在,类似于发生在大涎腺的肿瘤,在胸腔中是众所周知的。当它们出现在这个解剖区域时,这些肿瘤更常见于肺部。然而,这些主要影响胸腺的肿瘤的存在,虽然在文献中有所提及,但记录并不充分或广为人知。此外,与主要为恶性类型的原发性肺SGTs相反,这些发生在胸腺的肿瘤生物学特性范围更广,从良性到低级别和高级别恶性肿瘤都有。胸腺中SGTs的识别,尽管罕见,但对于正确处理治疗和预后很重要。在此,我们将讨论胸腺中已描述的众多良性和恶性SGTs,并强调这些肿瘤出现在胸腺区域时可能带来的困难。