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[参照手术操作的肺癌有限手术临床研究]

[Clinical study of limited operation of lung cancer with reference to the operative procedure].

作者信息

Akaogi E, Mitsui K, Sohara Y, Murayama H, Ogawa I, Ishikawa S, Morita R, Onizuka M, Nakagawa H, Hori M

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1989 Jul;37(7):1334-40.

PMID:2794591
Abstract

From 1977 to 1987, 27 cases of primary lung cancer were resected by the limited operation, 7 segmentectomy and 20 wedge resection. All cases of segmentectomy were considered to be potentially curative and 2 cases of them were X-ray negative early squamous cell carcinoma originated from the subsegmental bronchus. The mean tumor size of the other 5 peripheral cases performed segmentectomy was 37.6 mm in diameter. Two cases of segmentectomy died from cancer recurrence, but 2 cases are still alive more than 4.5 years after operation. All cases of wedge resection were originated peripherally, and 6 cases were thought to be potentially curative and the mean tumor size was 22.4 mm in diameter. Three cases of them died, 1 from the tumor metastasis and 2 from the other diseases than lung cancer, but the other cases undergone potentially curative wedge resection are alive without recurrence 1-3.6 years after operation. The limited operation should be indicated for the peripheral lung cancer without lymph node metastasis in the patients with marked cardiac and/or pulmonary impairment. The small nodule located in subpleural lung can be resected easily by the wedge resection, but the segmentectomy should be recommended for the tumor which is larger in size or located more deeply under the visceral pleura. Especially X-ray negative early squamous cell carcinoma of the bronchus can be curatively resected by the segmentectomy with lymph node dissection, if the tumor exists in the level of subsegmental bronchus or more peripherally. Palliative minimal resection for the advanced lung cancer seemed to be not effective of their long-surviving.

摘要

1977年至1987年期间,27例原发性肺癌患者接受了局限性手术,其中7例行肺段切除术,20例行楔形切除术。所有肺段切除术病例均被认为有可能治愈,其中2例为X线阴性的早期鳞状细胞癌,起源于亚段支气管。其他5例接受肺段切除术的外周型病例,肿瘤平均大小为直径37.6毫米。2例肺段切除术患者死于癌症复发,但有2例术后存活超过4.5年。所有楔形切除术病例均起源于外周,6例被认为有可能治愈,肿瘤平均大小为直径22.4毫米。其中3例死亡,1例死于肿瘤转移,2例死于肺癌以外的其他疾病,但其他接受了有可能治愈的楔形切除术的病例术后1至3.6年存活且无复发。对于有明显心脏和/或肺部功能损害且无淋巴结转移的外周型肺癌患者,应采用局限性手术。位于胸膜下肺的小结节可通过楔形切除术轻松切除,但对于较大或位于脏层胸膜下更深位置的肿瘤,应推荐肺段切除术。特别是支气管X线阴性的早期鳞状细胞癌,如果肿瘤位于亚段支气管水平或更外周,通过肺段切除术加淋巴结清扫可实现根治性切除。对于晚期肺癌的姑息性最小限度切除似乎对延长生存期无效。

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