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[用于羟基磷灰石牙种植体的下颌骨萎缩改善的组织学研究]

[Histological investigation of improvement of mandibular atrophy for application of hydroxyapatite dental implant].

作者信息

Uoshima K

出版信息

Kokubyo Gakkai Zasshi. 1989 Jun;56(2):314-46. doi: 10.5357/koubyou.56.314.

Abstract

UNLABELLED

The purpose of this study was to investigate the possibility of applying the hydroxyapatite dental implant to the atrophic mandible after alveolar ridge augmentation using hydroxyapatite granules. The lower P3, P4 and M1 of 3 mongrel dogs were extracted. At 30 weeks, alveolar ridge augmentation was performed with porous hydroxyapatite granules. Sixteen weeks later, hydroxyapatite dental implants were applied to the area. And 4 weeks later, the specimens were taken out and fixed by 10% formalin alcohol. They were embedded in polyester resin and prepared into undecalcified sections. And the sections were stained with toluidine blue to observe the surrounding tissue of the dental implants histologically under light microscopy.

RESULTS

  1. Bone formation was seen in most part of the intergranular spaces. However, in the buccal area, there were some spaces in which bone formation was entirely not observed. 2) At 4 weeks after implantation, almost all of the surface of the hydroxyapatite dental implants was attached to the surrounding osseous tissues. But in some parts of the implant surface, especially the buccal, fibrous connective tissue was seen. 3) These results provide a basis for the technique of hydroxyapatite dental implantation with porous hydroxyapatite granules in the atrophic mandibles after alveolar ridge augmentation.
摘要

未标记

本研究的目的是探讨在使用羟基磷灰石颗粒进行牙槽嵴增高后,将羟基磷灰石牙种植体应用于萎缩性下颌骨的可能性。拔除3只杂种犬的下颌P3、P4和M1。在30周时,用多孔羟基磷灰石颗粒进行牙槽嵴增高。16周后,将羟基磷灰石牙种植体应用于该区域。4周后,取出标本并用10%福尔马林酒精固定。将其嵌入聚酯树脂中制成不脱钙切片。切片用甲苯胺蓝染色,在光学显微镜下组织学观察牙种植体周围组织。

结果

1)在大部分颗粒间隙中可见骨形成。然而,在颊侧区域,有一些间隙完全未观察到骨形成。2)植入后4周,羟基磷灰石牙种植体的几乎所有表面都与周围骨组织附着。但在种植体表面的一些部位,尤其是颊侧,可见纤维结缔组织。3)这些结果为在牙槽嵴增高后萎缩性下颌骨中使用多孔羟基磷灰石颗粒进行羟基磷灰石牙种植技术提供了依据。

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