Grant R, Miller S, Simpson D, Lamey P J, Bone I
Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK.
J Neurol Neurosurg Psychiatry. 1989 Sep;52(9):1058-62. doi: 10.1136/jnnp.52.9.1058.
Bilateral chorda tympani section is an accepted treatment for troublesome sialorrhoea. Nevertheless the effects of this operation have been poorly studied. Twenty patients were studied with unilateral chorda tympani section and a healthy contralateral ear. The effects on ipsilateral and contralateral stimulated submandibular and parotid flow and taste recognition and detection thresholds were measured. Stimulated submandibular flow accounted for only 27% of the total salivary flow. Chorda tympani section had no effect on submandibular flow in seven patients and only reduced submandibular flow by approximately 54% in the remaining 13 patients. No significant effect was observed on ipsilateral parotid flow rate. Electrogustometric taste detection thresholds were more than twice the accepted upper limit of normal on the lesioned side and taste recognition thresholds were also markedly abnormal. Chorda tympani section alone is a poor method of reducing stimulated salivary flow.
双侧鼓索神经切断术是治疗难治性流涎的一种公认疗法。然而，该手术的效果尚未得到充分研究。对20例接受单侧鼓索神经切断术且对侧耳健康的患者进行了研究。测量了对同侧和对侧刺激下颌下腺和腮腺分泌以及味觉识别和检测阈值的影响。刺激下颌下腺分泌仅占唾液总分泌量的27%。鼓索神经切断术对7例患者的下颌下腺分泌无影响，仅使其余13例患者的下颌下腺分泌减少约54%。未观察到对同侧腮腺分泌速率有显著影响。病变侧的电味觉检测阈值超过正常公认上限的两倍以上，味觉识别阈值也明显异常。单独的鼓索神经切断术是减少刺激唾液分泌的一种欠佳方法。
