Voges G E, Tauschke E, Stöckle M, Alken P, Hohenfellner R
Department of Urology, University of Mainz Medical School, Federal Republic of Germany.
J Urol. 1989 Oct;142(4):972-4. doi: 10.1016/s0022-5347(17)38956-5.
A total of 164 patients with bladder tumors underwent preoperative staging by computerized tomography. All patients were previously untreated, or had undergone only transurethral biopsy or resection of the tumor before computerized tomography. The post-cystectomy histological stage was compared to the preoperative computerized tomography stage. Computerized tomography accuracy according to the tumor, nodes and metastasis classification was only 32.3%, whereas overstaging was found in 39.6% and understaging in 28.1% of the cases. In untouched tumors or after transurethral resection computerized tomography accuracy demonstrated no significant difference. Only 2 of 19 true positive lymph nodes were staged correctly. Of 10 suspicious nodes results of computerized tomography were false positive in 8. Computerized tomography is an unreliable method for accurate preoperative staging of bladder carcinoma. The indication for either an operation, chemotherapy or radiotherapy for the treatment of bladder neoplasms should not be based on computerized tomography findings.
共有164例膀胱肿瘤患者接受了术前计算机断层扫描分期。所有患者此前均未接受过治疗,或在计算机断层扫描前仅接受过经尿道活检或肿瘤切除术。将膀胱切除术后的组织学分期与术前计算机断层扫描分期进行比较。根据肿瘤、淋巴结和转移分类,计算机断层扫描的准确率仅为32.3%,而39.6%的病例存在分期过高,28.1%的病例存在分期过低。在未触及的肿瘤或经尿道切除术后,计算机断层扫描的准确率无显著差异。19个真正阳性淋巴结中只有2个分期正确。在10个可疑淋巴结中,计算机断层扫描结果有8个为假阳性。计算机断层扫描是一种不可靠的方法,无法准确进行膀胱癌术前分期。膀胱癌治疗的手术、化疗或放疗指征不应基于计算机断层扫描结果。