Tyson Mark D, Chang Sam S, Keegan Kirk A
Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Bladder (San Franc). 2016;3(2). doi: 10.14440/bladder.2016.89.
The effect of radical cystectomy and extended pelvic lymph node dissection (RC/PLND) on the survival of patients with locally advanced and/or regionally metastatic bladder cancer is unknown. However, emerging evidence suggests that there may be survival benefit to a subset of select patients with this disease who demonstrate a response to chemotherapy. This article will review the current literature on the role of RC/PLND in the consolidative treatment of locally advanced and regionally metastatic bladder cancer.
根治性膀胱切除术和扩大盆腔淋巴结清扫术(RC/PLND)对局部晚期和/或区域转移性膀胱癌患者生存的影响尚不清楚。然而,新出现的证据表明,对于部分对化疗有反应的该疾病患者,可能存在生存获益。本文将综述目前关于RC/PLND在局部晚期和区域转移性膀胱癌巩固治疗中作用的文献。