羟基磷灰石晶体上磷酸钙的生长。氟化物和膦酸盐的影响。

The growth of calcium phosphates on hydroxyapatite crystals. The effect of fluoride and phosphonate.

作者信息

Barone J P, Nancollas G H

出版信息

J Dent Res. 1978 May-Jun;57(5-6):735-42. doi: 10.1177/00220345780570051601.

DOI:10.1177/00220345780570051601

Abstract

The nature of the calcium phosphate phase which precipitates on hydroxyapatite seed crystals can be controlled by varying the HAP seed concentration. At low seed concentrations, dicalcium phosphate dihydrate (DCPD) is formed while at high seed levels a more basic phase precipitates. It has been found that fluoride ion increases the percentage of basic phase that crystallizes while ethylidenediphosphonic acid encourages the formation of DCPD. This behavior is explained by the competition between the nucleation of DCPD and the crystal growth on sites already present on the HAP seeds.

摘要

通过改变羟基磷灰石籽晶的浓度，可以控制沉淀在其上的磷酸钙相的性质。在低籽晶浓度下，会形成二水磷酸二钙（DCPD），而在高籽晶水平下，会沉淀出更碱性的相。已发现氟离子会增加结晶的碱性相的百分比，而亚乙基二膦酸则促进DCPD的形成。这种行为可以通过DCPD的成核与HAP籽晶上已存在的位点上的晶体生长之间的竞争来解释。