[针对小川血清型霍乱弧菌抗原的单克隆抗体]
[Monoclonal antibodies to antigens of cholera vibrios of the Ogava serovar].
作者信息
Burlakhova O S, Alekseeva L P, Novokhatskiĭ A S, Bichul' K G, Dranov I Iu
出版信息
Mikrobiol Zh (1978). 1989 May-Jun;51(3):56-60.
PMID:2796789
Abstract
A set of hybrids is obtained synthesizing monoclonal antibodies to the surface antigenic determinants of the choleric vibrio of the Ogava serovar. The antigenic structure of vibrios of the typical and atypical strains isolated from a man and from environmental objects is studied using a collection of highly specific immunoglobulins. The high-specific diagnostic preparations for identification of the 01-group cholera agent serovar may be created on their base.
摘要
通过合成针对小川血清型霍乱弧菌表面抗原决定簇的单克隆抗体，获得了一组杂交体。使用一系列高度特异性免疫球蛋白，研究了从人类和环境物体中分离出的典型和非典型菌株的弧菌抗原结构。在此基础上，可以制备用于鉴定01群霍乱病原体血清型的高特异性诊断制剂。
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