Petersen E J, Vermeersch P H, de Maat C E
Ned Tijdschr Geneeskd. 1989 Sep 23;133(38):1893-5.
We report the case of a young adult who visited us because of thrombocytopenia and bleeding, clinically and cytologically compatible with autoimmune thrombocytopenic purpura (AITP). He was seropositive for HIV-1 and therefore HIV associated thrombocytopenia was diagnosed. Recent insights in the pathogenesis of this novel disease entity are discussed. The treatment is the classical AITP therapy. It is important, however, to refrain from therapy as long as possible, since a significant part of these patients improve spontaneously. We conclude that HIV associated thrombocytopenia will be increasingly important in the differential diagnosis of bleeding disorders.
我们报告了一名年轻成年人的病例，该患者因血小板减少和出血前来就诊，临床和细胞学表现与自身免疫性血小板减少性紫癜（AITP）相符。他的HIV-1血清学呈阳性，因此被诊断为HIV相关血小板减少症。本文讨论了这种新型疾病实体发病机制的最新见解。治疗采用经典的AITP疗法。然而，重要的是尽可能长时间避免治疗，因为这些患者中有很大一部分会自发改善。我们得出结论，HIV相关血小板减少症在出血性疾病的鉴别诊断中将变得越来越重要。
