利用聚合物模拟生物功能以用于生物医学应用。
Mimicking biological functionality with polymers for biomedical applications.
作者信息
Green Jordan J, Elisseeff Jennifer H
机构信息
Translational Tissue Engineering Center, Departments of Biomedical Engineering and Ophthalmology, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
出版信息
Nature. 2016 Dec 14;540(7633):386-394. doi: 10.1038/nature21005.
Abstract
The vast opportunities for biomaterials design and functionality enabled by mimicking nature continue to stretch the limits of imagination. As both biological understanding and engineering capabilities develop, more sophisticated biomedical materials can be synthesized that have multifaceted chemical, biological and physical characteristics designed to achieve specific therapeutic goals. Mimicry is being used in the design of polymers for biomedical applications that are required locally in tissues, systemically throughout the body, and at the interface with tissues.
摘要
通过模仿自然实现的生物材料设计和功能的巨大机遇不断拓展着想象力的边界。随着生物学认知和工程能力的发展，可以合成出更复杂的生物医学材料，这些材料具有多方面的化学、生物学和物理特性，旨在实现特定的治疗目标。模仿正被用于设计用于生物医学应用的聚合物，这些聚合物在组织局部、全身以及组织界面处都有需求。
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