Sinclair B, Jackson R, Beaglehole R
Department of Community Health, School of Medicine, Auckland.
N Z Med J. 1989 Sep 27;102(876):491-3.
This paper examines the pattern of drug treatment of hypertension in Auckland in the period 1982 to 1987 using data from a representative sample of the adult population interviewed in 1982 and followed up in 1987. In 1982 the age standardised prevalence of antihypertensive treatment for people aged 40-64 years was 12.2% (95%Cl 10.4, 14.0) and in 1987 it was 10.2% (95%Cl 8.5, 11.8). Over the five year period of this study, 6% of the sample untreated in 1982 began treatment with antihypertensive medication, while 24% of those on drugs in 1982 had stopped treatment by 1987. The most common medications used in both 1982 and 1987 for hypertension were diuretics and beta blockers. Over the five year period diuretic use fell and beta blocker use remained constant. In 1982 3% of hypertensives were taking a calcium antagonist but in 1987 13% were on these drugs and a further 13% were using ACE inhibitors. This study suggests that the prevalence of drug treatment for hypertension has plateaued in New Zealand; coincidentally there is a trend towards use of more expensive drugs.
本文利用1982年对成年人口代表性样本进行访谈并于1987年进行随访的数据，研究了1982年至1987年奥克兰高血压药物治疗模式。1982年，40 - 64岁人群的抗高血压治疗年龄标准化患病率为12.2%（95%置信区间10.4, 14.0），1987年为10.2%（95%置信区间8.5, 11.8）。在本研究的五年期间，1982年未接受治疗的样本中有6%开始使用抗高血压药物治疗，而1982年正在服药的人群中有24%到1987年已停止治疗。1982年和1987年治疗高血压最常用的药物是利尿剂和β受体阻滞剂。在这五年期间，利尿剂的使用减少，β受体阻滞剂的使用保持不变。1982年，3%的高血压患者服用钙拮抗剂，但1987年有13%的患者服用这些药物，另有13%的患者使用血管紧张素转换酶抑制剂。这项研究表明，新西兰高血压药物治疗的患病率已趋于平稳；巧合的是，有使用更昂贵药物的趋势。
